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Influence of haloperidol on the /sup 3/H-leucine incorporation in incretory organs of the mouse

Journal Article:

Abstract

The /sup 3/H-leucine incorporation in proteins of incretory organs of the mouse, the exocrine pancreas, and the renal tubuli was studied autoradiographically after administration of therapylike doses of the neuroleptic drug Haloperidol. With exception of the pancreas, a dosage dependent increase of the /sup 3/H-leucine incorporation was observed in the treated animals. The results reveal an activation of the hypothalamus-hypophysis-adrenocortical system due to a 10-days administration of Haloperidol. These results are in conformity with former ones in brain and liver.
Authors:
Lange, E; Hackenberg, P [1] 
  1. Bezirksnervenklinik, Schwerin (German Democratic Republic)
Publication Date:
Jan 01, 1978
Product Type:
Journal Article
Reference Number:
AIX-10-448669; EDB-79-075496
Resource Relation:
Journal Name: Zentralbl. Allgem. Pathol. Pathol. Anat.; (German Democratic Republic); Journal Volume: 122:5
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; LEUCINE; TRITIUM COMPOUNDS; PROTEINS; LABELLING; RADIONUCLIDE KINETICS; AUTORADIOGRAPHY; COMPARATIVE EVALUATIONS; MICE; PANCREAS; PSYCHOTROPIC DRUGS; TRACER TECHNIQUES; TUBULES; AMINO ACIDS; ANIMALS; BODY; CARBOXYLIC ACIDS; DIGESTIVE SYSTEM; DRUGS; ENDOCRINE GLANDS; GLANDS; ISOTOPE APPLICATIONS; KIDNEYS; LABELLED COMPOUNDS; MAMMALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RODENTS; VERTEBRATES; 560172* - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987); 550601 - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6332704
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: ZAPPA
Submitting Site:
INIS
Size:
Pages: 496-501
Announcement Date:

Journal Article:

Citation Formats

Lange, E, and Hackenberg, P. Influence of haloperidol on the /sup 3/H-leucine incorporation in incretory organs of the mouse. Germany: N. p., 1978. Web.
Lange, E, & Hackenberg, P. Influence of haloperidol on the /sup 3/H-leucine incorporation in incretory organs of the mouse. Germany.
Lange, E, and Hackenberg, P. 1978. "Influence of haloperidol on the /sup 3/H-leucine incorporation in incretory organs of the mouse." Germany.
@misc{etde_6332704,
title = {Influence of haloperidol on the /sup 3/H-leucine incorporation in incretory organs of the mouse}
author = {Lange, E, and Hackenberg, P}
abstractNote = {The /sup 3/H-leucine incorporation in proteins of incretory organs of the mouse, the exocrine pancreas, and the renal tubuli was studied autoradiographically after administration of therapylike doses of the neuroleptic drug Haloperidol. With exception of the pancreas, a dosage dependent increase of the /sup 3/H-leucine incorporation was observed in the treated animals. The results reveal an activation of the hypothalamus-hypophysis-adrenocortical system due to a 10-days administration of Haloperidol. These results are in conformity with former ones in brain and liver.}
journal = {Zentralbl. Allgem. Pathol. Pathol. Anat.; (German Democratic Republic)}
volume = {122:5}
journal type = {AC}
place = {Germany}
year = {1978}
month = {Jan}
}