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Disposal of coal and hematite dusts inhaled successively

Abstract

Rabbits and rats were exposed in a chamber to coal (20,000 and 10,000 particles/ml) and hematite (20,000 and 37,000 particles/ml) in succession to follow deposition and clearance by color. Exposures were 5 days/wk, 20 hr/day. Generally, there was dust widely but not uniformly distributed in peripheral alveoli, tending to aggregate and clump in more proximal alveoli with time. There was initial nonuniform distribution more uniform with exposure time. Aggregation mostly through phagocyte activities and more evident in rabbits than rats was observed. There was eventual mixing of two dusts inhaled up to 7 months apart. Dust deposited last is cleared first because of less tortuous route.
Authors:
Publication Date:
Jan 01, 1958
Product Type:
Journal Article
Reference Number:
EDB-79-075546
Resource Relation:
Journal Name: J. Pathol. Bacteriol.; (United Kingdom); Journal Volume: 75
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; COAL; LUNG CLEARANCE; HEMATITE; BIOLOGICAL EFFECTS; DUSTS; RABBITS; RATS; RESPIRATORY SYSTEM DISEASES; ANIMALS; CARBONACEOUS MATERIALS; CHALCOGENIDES; CLEARANCE; DISEASES; ENERGY SOURCES; EXCRETION; FOSSIL FUELS; FUELS; IRON COMPOUNDS; IRON ORES; IRON OXIDES; MAMMALS; MINERALS; ORES; OXIDES; OXYGEN COMPOUNDS; RODENTS; TRANSITION ELEMENT COMPOUNDS; VERTEBRATES; 560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
OSTI ID:
6332469
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JPBAA
Submitting Site:
TIC
Size:
Pages: 113-126
Announcement Date:
Jun 01, 1979

Citation Formats

Heppleston, A G. Disposal of coal and hematite dusts inhaled successively. United Kingdom: N. p., 1958. Web. doi:10.1002/path.1700750114.
Heppleston, A G. Disposal of coal and hematite dusts inhaled successively. United Kingdom. doi:10.1002/path.1700750114.
Heppleston, A G. 1958. "Disposal of coal and hematite dusts inhaled successively." United Kingdom. doi:10.1002/path.1700750114. https://www.osti.gov/servlets/purl/10.1002/path.1700750114.
@misc{etde_6332469,
title = {Disposal of coal and hematite dusts inhaled successively}
author = {Heppleston, A G}
abstractNote = {Rabbits and rats were exposed in a chamber to coal (20,000 and 10,000 particles/ml) and hematite (20,000 and 37,000 particles/ml) in succession to follow deposition and clearance by color. Exposures were 5 days/wk, 20 hr/day. Generally, there was dust widely but not uniformly distributed in peripheral alveoli, tending to aggregate and clump in more proximal alveoli with time. There was initial nonuniform distribution more uniform with exposure time. Aggregation mostly through phagocyte activities and more evident in rabbits than rats was observed. There was eventual mixing of two dusts inhaled up to 7 months apart. Dust deposited last is cleared first because of less tortuous route.}
doi = {10.1002/path.1700750114}
journal = {J. Pathol. Bacteriol.; (United Kingdom)}
volume = {75}
journal type = {AC}
place = {United Kingdom}
year = {1958}
month = {Jan}
}