Abstract
In the framework of an EC research programme on the health risks of environmental chemicals, the Istituto Superiore di Sanita` co-ordinated, in 1993-1996, a project on the biological effects of benzene and petroleum fuels. Seven laboratories from six European countries collaborated in the biological monitoring of selected population with occupational exposure to petrochemicals. Several markers of early biological effect were applied together with environmental and personal exposure monitoring techniques. An epidemiological retrospective mortality study was also carried out on Italian filling station attendants. The results obtained highlighted an excess of genetic damage in some of the study populations, compared to matched unexposed controls. Even though these results do not allow a reliable risk estimation, the possible prognostic significance of cytogenetic damage for future cancer onset, together with some alerting findings from the mortality study, suggest that low dose exposures to benzene and petroleum fuels may retain some toxicological significance.
Carere, A;
Crebelli, R
[1]
- ed.; Istituto Superiore di Sanita`, Rome (Italy). Lab. di Tossicologia Comparata ed Ecotossicologia
Citation Formats
Carere, A, and Crebelli, R.
Biomonitoring of human population exposed to petroleum fuels with special consideration of the role of benzene as a genotoxic component. Report of the EC Environment programme. Project EV5V-CT.
Italy: N. p.,
1997.
Web.
Carere, A, & Crebelli, R.
Biomonitoring of human population exposed to petroleum fuels with special consideration of the role of benzene as a genotoxic component. Report of the EC Environment programme. Project EV5V-CT.
Italy.
Carere, A, and Crebelli, R.
1997.
"Biomonitoring of human population exposed to petroleum fuels with special consideration of the role of benzene as a genotoxic component. Report of the EC Environment programme. Project EV5V-CT."
Italy.
@misc{etde_632763,
title = {Biomonitoring of human population exposed to petroleum fuels with special consideration of the role of benzene as a genotoxic component. Report of the EC Environment programme. Project EV5V-CT}
author = {Carere, A, and Crebelli, R}
abstractNote = {In the framework of an EC research programme on the health risks of environmental chemicals, the Istituto Superiore di Sanita` co-ordinated, in 1993-1996, a project on the biological effects of benzene and petroleum fuels. Seven laboratories from six European countries collaborated in the biological monitoring of selected population with occupational exposure to petrochemicals. Several markers of early biological effect were applied together with environmental and personal exposure monitoring techniques. An epidemiological retrospective mortality study was also carried out on Italian filling station attendants. The results obtained highlighted an excess of genetic damage in some of the study populations, compared to matched unexposed controls. Even though these results do not allow a reliable risk estimation, the possible prognostic significance of cytogenetic damage for future cancer onset, together with some alerting findings from the mortality study, suggest that low dose exposures to benzene and petroleum fuels may retain some toxicological significance.}
place = {Italy}
year = {1997}
month = {Dec}
}
title = {Biomonitoring of human population exposed to petroleum fuels with special consideration of the role of benzene as a genotoxic component. Report of the EC Environment programme. Project EV5V-CT}
author = {Carere, A, and Crebelli, R}
abstractNote = {In the framework of an EC research programme on the health risks of environmental chemicals, the Istituto Superiore di Sanita` co-ordinated, in 1993-1996, a project on the biological effects of benzene and petroleum fuels. Seven laboratories from six European countries collaborated in the biological monitoring of selected population with occupational exposure to petrochemicals. Several markers of early biological effect were applied together with environmental and personal exposure monitoring techniques. An epidemiological retrospective mortality study was also carried out on Italian filling station attendants. The results obtained highlighted an excess of genetic damage in some of the study populations, compared to matched unexposed controls. Even though these results do not allow a reliable risk estimation, the possible prognostic significance of cytogenetic damage for future cancer onset, together with some alerting findings from the mortality study, suggest that low dose exposures to benzene and petroleum fuels may retain some toxicological significance.}
place = {Italy}
year = {1997}
month = {Dec}
}