Abstract
Radioimmunologic technique of double antibodies was used for the determination of alphafetoprotein (AFP) concentrations in blood serum samples from 223 healthy, pregnant women with single pregnancies and in amniotic fluid samples from 43 donors. The gestational age during samples collection was 10 to 25 weeks. The AFP preparation for the test was supplied by the International Agency of Cancer Research, anti-AFP antibodies produced by Behringwerke and personally produced rabbit antiglobulin antibodies. The results of the AFP determinations in the blood and amniotic fluid samples were presented in tables in form of medians. The serum AFP concentrations overranging the double medians value were met in 8.5%, overranging the triple medians - in 2.6%. Repeat determinations decreased the number of false positive results for about 50%. The results permit to issue a conclusion that the used technique is fully applicable for scan examinations in prenatal diagnosis of fetal nervous system malformations.
Skalba, P;
Krupa, B;
Rozmus, M;
Brudnik, K;
Kokocinska, D;
Rajs, M
[1]
- Slaska Akademia Medyczna, Katowice (Poland)
Citation Formats
Skalba, P, Krupa, B, Rozmus, M, Brudnik, K, Kokocinska, D, and Rajs, M.
Radioimmunologic determination of alphafetoproteins concentration in blood serum samples and in the amniotic fluid in healthy pregnant women in the 2 trimester of pregnancy.
Poland: N. p.,
1980.
Web.
Skalba, P, Krupa, B, Rozmus, M, Brudnik, K, Kokocinska, D, & Rajs, M.
Radioimmunologic determination of alphafetoproteins concentration in blood serum samples and in the amniotic fluid in healthy pregnant women in the 2 trimester of pregnancy.
Poland.
Skalba, P, Krupa, B, Rozmus, M, Brudnik, K, Kokocinska, D, and Rajs, M.
1980.
"Radioimmunologic determination of alphafetoproteins concentration in blood serum samples and in the amniotic fluid in healthy pregnant women in the 2 trimester of pregnancy."
Poland.
@misc{etde_6327116,
title = {Radioimmunologic determination of alphafetoproteins concentration in blood serum samples and in the amniotic fluid in healthy pregnant women in the 2 trimester of pregnancy}
author = {Skalba, P, Krupa, B, Rozmus, M, Brudnik, K, Kokocinska, D, and Rajs, M}
abstractNote = {Radioimmunologic technique of double antibodies was used for the determination of alphafetoprotein (AFP) concentrations in blood serum samples from 223 healthy, pregnant women with single pregnancies and in amniotic fluid samples from 43 donors. The gestational age during samples collection was 10 to 25 weeks. The AFP preparation for the test was supplied by the International Agency of Cancer Research, anti-AFP antibodies produced by Behringwerke and personally produced rabbit antiglobulin antibodies. The results of the AFP determinations in the blood and amniotic fluid samples were presented in tables in form of medians. The serum AFP concentrations overranging the double medians value were met in 8.5%, overranging the triple medians - in 2.6%. Repeat determinations decreased the number of false positive results for about 50%. The results permit to issue a conclusion that the used technique is fully applicable for scan examinations in prenatal diagnosis of fetal nervous system malformations.}
journal = []
volume = {51:10}
journal type = {AC}
place = {Poland}
year = {1980}
month = {Jan}
}
title = {Radioimmunologic determination of alphafetoproteins concentration in blood serum samples and in the amniotic fluid in healthy pregnant women in the 2 trimester of pregnancy}
author = {Skalba, P, Krupa, B, Rozmus, M, Brudnik, K, Kokocinska, D, and Rajs, M}
abstractNote = {Radioimmunologic technique of double antibodies was used for the determination of alphafetoprotein (AFP) concentrations in blood serum samples from 223 healthy, pregnant women with single pregnancies and in amniotic fluid samples from 43 donors. The gestational age during samples collection was 10 to 25 weeks. The AFP preparation for the test was supplied by the International Agency of Cancer Research, anti-AFP antibodies produced by Behringwerke and personally produced rabbit antiglobulin antibodies. The results of the AFP determinations in the blood and amniotic fluid samples were presented in tables in form of medians. The serum AFP concentrations overranging the double medians value were met in 8.5%, overranging the triple medians - in 2.6%. Repeat determinations decreased the number of false positive results for about 50%. The results permit to issue a conclusion that the used technique is fully applicable for scan examinations in prenatal diagnosis of fetal nervous system malformations.}
journal = []
volume = {51:10}
journal type = {AC}
place = {Poland}
year = {1980}
month = {Jan}
}