Abstract
Changes in lung phospholipids of golden hamsters exposed to 2 mg/mT coal fly ash for 180 days, 7 days/week, 20 hours/day were examined. In the exposed group the amount of phospholipids in lavaged lung organ increased significantly compared with the control group, but in pulmonary surfactant did not. As regards lipid composition of phospholipids in lavaged lung organ, phosphatidylcholine was slightly increased but sphingomyelin was decreased by exposure. Some significant changes in fatty acid composition of phospholipids were observed between exposed and control group. In pulmonary surfactant, palmitic acid showed no change but myristic acid and oleic acid decreased. On the other hand, in lavaged lung organ, palmitic acid increased but stearic acid and decosatetraenoic acid decreased. Arachidonic acid composition increased in both parts of lung. An increase in the proportion of polyunsaturated fatty acid in whole fatty acid of phospholipids was found in pulmonary surfactant of exposed hamsters. 24 refs., 2 figs., 3 tabs.
Citation Formats
Nishimura, I, Negishi, T, and Kamihira, M.
Effects of chronic fly ash exposure on golden hamsters: changes in lung phospholipids and their fatty acid composition as a result of inhalation.
Japan: N. p.,
1986.
Web.
Nishimura, I, Negishi, T, & Kamihira, M.
Effects of chronic fly ash exposure on golden hamsters: changes in lung phospholipids and their fatty acid composition as a result of inhalation.
Japan.
Nishimura, I, Negishi, T, and Kamihira, M.
1986.
"Effects of chronic fly ash exposure on golden hamsters: changes in lung phospholipids and their fatty acid composition as a result of inhalation."
Japan.
@misc{etde_6311551,
title = {Effects of chronic fly ash exposure on golden hamsters: changes in lung phospholipids and their fatty acid composition as a result of inhalation}
author = {Nishimura, I, Negishi, T, and Kamihira, M}
abstractNote = {Changes in lung phospholipids of golden hamsters exposed to 2 mg/mT coal fly ash for 180 days, 7 days/week, 20 hours/day were examined. In the exposed group the amount of phospholipids in lavaged lung organ increased significantly compared with the control group, but in pulmonary surfactant did not. As regards lipid composition of phospholipids in lavaged lung organ, phosphatidylcholine was slightly increased but sphingomyelin was decreased by exposure. Some significant changes in fatty acid composition of phospholipids were observed between exposed and control group. In pulmonary surfactant, palmitic acid showed no change but myristic acid and oleic acid decreased. On the other hand, in lavaged lung organ, palmitic acid increased but stearic acid and decosatetraenoic acid decreased. Arachidonic acid composition increased in both parts of lung. An increase in the proportion of polyunsaturated fatty acid in whole fatty acid of phospholipids was found in pulmonary surfactant of exposed hamsters. 24 refs., 2 figs., 3 tabs.}
journal = []
volume = {485023}
journal type = {AC}
place = {Japan}
year = {1986}
month = {Jan}
}
title = {Effects of chronic fly ash exposure on golden hamsters: changes in lung phospholipids and their fatty acid composition as a result of inhalation}
author = {Nishimura, I, Negishi, T, and Kamihira, M}
abstractNote = {Changes in lung phospholipids of golden hamsters exposed to 2 mg/mT coal fly ash for 180 days, 7 days/week, 20 hours/day were examined. In the exposed group the amount of phospholipids in lavaged lung organ increased significantly compared with the control group, but in pulmonary surfactant did not. As regards lipid composition of phospholipids in lavaged lung organ, phosphatidylcholine was slightly increased but sphingomyelin was decreased by exposure. Some significant changes in fatty acid composition of phospholipids were observed between exposed and control group. In pulmonary surfactant, palmitic acid showed no change but myristic acid and oleic acid decreased. On the other hand, in lavaged lung organ, palmitic acid increased but stearic acid and decosatetraenoic acid decreased. Arachidonic acid composition increased in both parts of lung. An increase in the proportion of polyunsaturated fatty acid in whole fatty acid of phospholipids was found in pulmonary surfactant of exposed hamsters. 24 refs., 2 figs., 3 tabs.}
journal = []
volume = {485023}
journal type = {AC}
place = {Japan}
year = {1986}
month = {Jan}
}