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Treatment of intractable cancer by radiotherapy

Abstract

Intraoperative irradiation, thermotherapy, hypoxic cell sensitizer, and neutron brachytherapy were used for locally advanced cancer and value and limitations of these therapies were discussed. Intraoperative irradiation was mainly used for cancers of the gastro-intestinal tract. In stage I gastric cancers, no difference in the five-year survival rates was found between the groups with and without intraoperative irradiation. In gastric cancers of stage II or more, intraoperative irradiation had a favourable effect. Thermotherapy was applied to superficial radio-resistant cancer by the use of a thermal system of microwave- and radio-frequency heating. This treatment induced disappearance of approximately 50% of tumor. For the treatment with hypoxic cell sensitizer, studies of phase I and II with Misonidazole were conducted; from these results, the protocol was made for phase III study of esophagus cancer, lung cancer, head and neck cancer, uterus cancer, and brain cancer. Brachytherapy using /sup 252/Cf was also developed for locally advanced cancer.
Authors:
Abe, M [1] 
  1. Kyoto Univ. (Japan). Faculty of Medicine
Publication Date:
Jul 01, 1981
Product Type:
Journal Article
Reference Number:
AIX-14-750712; EDB-83-097780
Resource Relation:
Journal Name: Koseisho Gan Kenkyu Joseikin Ni Yoru Kenkyu Hokoku; (Japan); Journal Volume: 1980
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; NEUTRON THERAPY; BRAIN; ESOPHAGUS; FAST NEUTRONS; HYPERTHERMIA; LUNGS; PATIENTS; RADIOSENSITIVITY; RESPONSE MODIFYING FACTORS; UTERUS; BARYONS; BODY; BODY TEMPERATURE; CENTRAL NERVOUS SYSTEM; DIGESTIVE SYSTEM; DISEASES; ELEMENTARY PARTICLES; FEMALE GENITALS; FERMIONS; HADRONS; MEDICINE; NEOPLASMS; NERVOUS SYSTEM; NEUTRONS; NUCLEAR MEDICINE; NUCLEONS; ORGANS; RADIOLOGY; RADIOTHERAPY; RESPIRATORY SYSTEM; THERAPY; 550603* - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
6297881
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KKJHD
Submitting Site:
HEDB
Size:
Pages: 334-351
Announcement Date:
Apr 01, 1983

Citation Formats

Abe, M. Treatment of intractable cancer by radiotherapy. Japan: N. p., 1981. Web.
Abe, M. Treatment of intractable cancer by radiotherapy. Japan.
Abe, M. 1981. "Treatment of intractable cancer by radiotherapy." Japan.
@misc{etde_6297881,
title = {Treatment of intractable cancer by radiotherapy}
author = {Abe, M}
abstractNote = {Intraoperative irradiation, thermotherapy, hypoxic cell sensitizer, and neutron brachytherapy were used for locally advanced cancer and value and limitations of these therapies were discussed. Intraoperative irradiation was mainly used for cancers of the gastro-intestinal tract. In stage I gastric cancers, no difference in the five-year survival rates was found between the groups with and without intraoperative irradiation. In gastric cancers of stage II or more, intraoperative irradiation had a favourable effect. Thermotherapy was applied to superficial radio-resistant cancer by the use of a thermal system of microwave- and radio-frequency heating. This treatment induced disappearance of approximately 50% of tumor. For the treatment with hypoxic cell sensitizer, studies of phase I and II with Misonidazole were conducted; from these results, the protocol was made for phase III study of esophagus cancer, lung cancer, head and neck cancer, uterus cancer, and brain cancer. Brachytherapy using /sup 252/Cf was also developed for locally advanced cancer.}
journal = []
volume = {1980}
journal type = {AC}
place = {Japan}
year = {1981}
month = {Jul}
}