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Measurement of regional hepatic blood flow by scintiphotosplenoportography

Abstract

A new technique for estimating regional hepatic blood flow using the inert gas washout technique and scintillation camera following injection of /sup 133/Xe into the spleen is presented. This technique is easily, rapidly and repeatedly performed and permits the measurement of nutrient hepatic tissue blood flow. Measurement of regional hepatic blood flow in right and/or left lobes was performed in 28 patients. In all but one patient the right lobar flow value was equal to or greater than the left one. The right lobar flow was 86.20 +- 12.83 ml/100 gm/min in 3 patients without liver disease, 75.12 +- 14.54 ml/100 gm/min in 12 with chronic hepatitis and 51.24 +- 17.13 ml/100 gm/min in 11 with liver cirrhosis. This result suggests that hepatic tissue blood flow is significantly decreased in patients with liver cirrhosis. Scintillation camera images of initial xenon distribution in combination with monitor of washout curves over the liver also provide more information on the presence of extra- and intrahepatic shunts. Therefore, this technique appears to be clinically useful in evaluation of hemodynamic phenomena associated with liver diseases.
Authors:
Kashiwagi, T; Kimura, K; Kamada, T; Abe, H [1] 
  1. Osaka Univ. (Japan). Dept. of Radiology and Nuclear Medicine
Publication Date:
Aug 01, 1978
Product Type:
Journal Article
Reference Number:
AIX-10-449044; EDB-79-075273
Resource Relation:
Journal Name: Acta Hepato-Gastroenterol.; (Germany, Federal Republic of); Journal Volume: 25:4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD FLOW; SCINTISCANNING; LIVER CIRRHOSIS; HYPERTENSION; PATIENTS; TRACER TECHNIQUES; XENON 133; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARDIOVASCULAR DISEASES; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM DISEASES; DISEASES; EVEN-ODD NUCLEI; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; NUCLEI; RADIOISOTOPE SCANNING; RADIOISOTOPES; SYMPTOMS; VASCULAR DISEASES; XENON ISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6288742
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: AHGSB
Submitting Site:
INIS
Size:
Pages: 260-266
Announcement Date:
May 01, 1979

Citation Formats

Kashiwagi, T, Kimura, K, Kamada, T, and Abe, H. Measurement of regional hepatic blood flow by scintiphotosplenoportography. Germany: N. p., 1978. Web.
Kashiwagi, T, Kimura, K, Kamada, T, & Abe, H. Measurement of regional hepatic blood flow by scintiphotosplenoportography. Germany.
Kashiwagi, T, Kimura, K, Kamada, T, and Abe, H. 1978. "Measurement of regional hepatic blood flow by scintiphotosplenoportography." Germany.
@misc{etde_6288742,
title = {Measurement of regional hepatic blood flow by scintiphotosplenoportography}
author = {Kashiwagi, T, Kimura, K, Kamada, T, and Abe, H}
abstractNote = {A new technique for estimating regional hepatic blood flow using the inert gas washout technique and scintillation camera following injection of /sup 133/Xe into the spleen is presented. This technique is easily, rapidly and repeatedly performed and permits the measurement of nutrient hepatic tissue blood flow. Measurement of regional hepatic blood flow in right and/or left lobes was performed in 28 patients. In all but one patient the right lobar flow value was equal to or greater than the left one. The right lobar flow was 86.20 +- 12.83 ml/100 gm/min in 3 patients without liver disease, 75.12 +- 14.54 ml/100 gm/min in 12 with chronic hepatitis and 51.24 +- 17.13 ml/100 gm/min in 11 with liver cirrhosis. This result suggests that hepatic tissue blood flow is significantly decreased in patients with liver cirrhosis. Scintillation camera images of initial xenon distribution in combination with monitor of washout curves over the liver also provide more information on the presence of extra- and intrahepatic shunts. Therefore, this technique appears to be clinically useful in evaluation of hemodynamic phenomena associated with liver diseases.}
journal = []
volume = {25:4}
journal type = {AC}
place = {Germany}
year = {1978}
month = {Aug}
}