Abstract
Data from a variety of inhalation exposure studies have been presented and compared in an effort to better understand the deposition, clearance, and long-term retention of diesel particles in the lung. In response to observations of the apparent linear increase of the lung burden after inhalation of high concentrations of diesel exhaust particulates (250, 750, 1500, and 6000 ..mu..g/m/sup 3/) for a long period of time, a mathematical model of particulate transport in the respiratory system was developed to evaluate and interpret the experimental findings. Tracing the diesel particles was accomplished by tagging the particles with /sup 14/C which were inhaled by test animals. Results of the experiments indicate that low doses of diesel particulate material are rapidly cleared by the lung defense system but that species differences do exist in clearance and retention mechanics.
Citation Formats
Vostal, J J, Schreck, R M, Lee, P S, Chan, T L, and Soderholm, S C.
Deposition and clearance of diesel particles from the lung.
Netherlands: N. p.,
1982.
Web.
Vostal, J J, Schreck, R M, Lee, P S, Chan, T L, & Soderholm, S C.
Deposition and clearance of diesel particles from the lung.
Netherlands.
Vostal, J J, Schreck, R M, Lee, P S, Chan, T L, and Soderholm, S C.
1982.
"Deposition and clearance of diesel particles from the lung."
Netherlands.
@misc{etde_6267636,
title = {Deposition and clearance of diesel particles from the lung}
author = {Vostal, J J, Schreck, R M, Lee, P S, Chan, T L, and Soderholm, S C}
abstractNote = {Data from a variety of inhalation exposure studies have been presented and compared in an effort to better understand the deposition, clearance, and long-term retention of diesel particles in the lung. In response to observations of the apparent linear increase of the lung burden after inhalation of high concentrations of diesel exhaust particulates (250, 750, 1500, and 6000 ..mu..g/m/sup 3/) for a long period of time, a mathematical model of particulate transport in the respiratory system was developed to evaluate and interpret the experimental findings. Tracing the diesel particles was accomplished by tagging the particles with /sup 14/C which were inhaled by test animals. Results of the experiments indicate that low doses of diesel particulate material are rapidly cleared by the lung defense system but that species differences do exist in clearance and retention mechanics.}
journal = []
volume = {10}
place = {Netherlands}
year = {1982}
month = {Jan}
}
title = {Deposition and clearance of diesel particles from the lung}
author = {Vostal, J J, Schreck, R M, Lee, P S, Chan, T L, and Soderholm, S C}
abstractNote = {Data from a variety of inhalation exposure studies have been presented and compared in an effort to better understand the deposition, clearance, and long-term retention of diesel particles in the lung. In response to observations of the apparent linear increase of the lung burden after inhalation of high concentrations of diesel exhaust particulates (250, 750, 1500, and 6000 ..mu..g/m/sup 3/) for a long period of time, a mathematical model of particulate transport in the respiratory system was developed to evaluate and interpret the experimental findings. Tracing the diesel particles was accomplished by tagging the particles with /sup 14/C which were inhaled by test animals. Results of the experiments indicate that low doses of diesel particulate material are rapidly cleared by the lung defense system but that species differences do exist in clearance and retention mechanics.}
journal = []
volume = {10}
place = {Netherlands}
year = {1982}
month = {Jan}
}