Abstract
Here a new bone marrow imaging agent, {sup 99m}Tc-polyphase liposomes ({sup 99m}Tc-PL) was reported. It was labelled with {sup 99m}Tc using the stannous chloride method, the labelling rate was over 95% (n = 20). Imaging studies of the bone marrow in rabbits showed that the bone marrow was visulized at 30 min, and was more distinct at 1 {approx} 3.5 h. Tissue distribution of {sup 99m}Tc-PL in rabbits (n = 9) revealed that the bone marrow uptake rate of {sup 99m}Tc-PL was greater than bone uptake rate at three time phases (6.6%, 1.5h, 14%, 3.5h, 5%, 24h versus 0.6%, 1.5h, 0,4%, 3.5h, 0.4%, 24h, P < 0.01). Blood clearence rate was 84% at 45 min, and over 98% at 24 hours. This study shown that {sup 99m}Tc-PL may be useful as a new bone marrow imaging agent.
Baofa, Yu
[1]
- China-Japan Friendship Hospital, Beijing, BJ (China). Cancer Hospital; and others
Citation Formats
Baofa, Yu.
A new bone marrow imaging agent: preparation of sup 99m Tc-polyphase liposomes and its animals experiment.
China: N. p.,
1989.
Web.
Baofa, Yu.
A new bone marrow imaging agent: preparation of sup 99m Tc-polyphase liposomes and its animals experiment.
China.
Baofa, Yu.
1989.
"A new bone marrow imaging agent: preparation of sup 99m Tc-polyphase liposomes and its animals experiment."
China.
@misc{etde_6258069,
title = {A new bone marrow imaging agent: preparation of sup 99m Tc-polyphase liposomes and its animals experiment}
author = {Baofa, Yu}
abstractNote = {Here a new bone marrow imaging agent, {sup 99m}Tc-polyphase liposomes ({sup 99m}Tc-PL) was reported. It was labelled with {sup 99m}Tc using the stannous chloride method, the labelling rate was over 95% (n = 20). Imaging studies of the bone marrow in rabbits showed that the bone marrow was visulized at 30 min, and was more distinct at 1 {approx} 3.5 h. Tissue distribution of {sup 99m}Tc-PL in rabbits (n = 9) revealed that the bone marrow uptake rate of {sup 99m}Tc-PL was greater than bone uptake rate at three time phases (6.6%, 1.5h, 14%, 3.5h, 5%, 24h versus 0.6%, 1.5h, 0,4%, 3.5h, 0.4%, 24h, P < 0.01). Blood clearence rate was 84% at 45 min, and over 98% at 24 hours. This study shown that {sup 99m}Tc-PL may be useful as a new bone marrow imaging agent.}
journal = []
volume = {9:3}
journal type = {AC}
place = {China}
year = {1989}
month = {Aug}
}
title = {A new bone marrow imaging agent: preparation of sup 99m Tc-polyphase liposomes and its animals experiment}
author = {Baofa, Yu}
abstractNote = {Here a new bone marrow imaging agent, {sup 99m}Tc-polyphase liposomes ({sup 99m}Tc-PL) was reported. It was labelled with {sup 99m}Tc using the stannous chloride method, the labelling rate was over 95% (n = 20). Imaging studies of the bone marrow in rabbits showed that the bone marrow was visulized at 30 min, and was more distinct at 1 {approx} 3.5 h. Tissue distribution of {sup 99m}Tc-PL in rabbits (n = 9) revealed that the bone marrow uptake rate of {sup 99m}Tc-PL was greater than bone uptake rate at three time phases (6.6%, 1.5h, 14%, 3.5h, 5%, 24h versus 0.6%, 1.5h, 0,4%, 3.5h, 0.4%, 24h, P < 0.01). Blood clearence rate was 84% at 45 min, and over 98% at 24 hours. This study shown that {sup 99m}Tc-PL may be useful as a new bone marrow imaging agent.}
journal = []
volume = {9:3}
journal type = {AC}
place = {China}
year = {1989}
month = {Aug}
}