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Aerosol lung inhalation scintigraphy in normal subjects

Journal Article:

Abstract

We previously reported basic and clinical evaluation of aerosol lung inhalation scintigraphy with /sup 99m/Tc-millimicrosphere albumin (milli MISA) and concluded aerosol inhalation scintigraphy with /sup 99m/Tc-milli MISA was useful for routine examination. But central airway deposit of aerosol particles was found in not only the patients with chronic obstructive pulmonary disease (COPD) but also normal subjects. So we performed aerosol inhalation scintigraphy in normal subjects and evaluated their scintigrams. The subjects had normal values of FEVsub(1.0)% (more than 70%) in lung function tests, no abnormal findings in chest X-ray films and no symptoms and signs. The findings of aerosol inhalation scintigrams in them were classified into 3 patterns; type I: homogeneous distribution without central airway deposit, type II: homogeneous distribution with central airway deposit, type III: inhomogeneous distribution. These patterns were compared with lung function tests. There was no significant correlation between type I and type II in lung function tests. Type III was different from type I and type II in inhomogeneous distribution. This finding showed no correlation with %VC, FEVsub(1.0)%, MMF, V radical50 and V radical50/V radical25, but good correlation with V radical25 in a maximum forced expiratory flow-volume curve. Flow-volume curve is one of the sensitive methods  More>>
Publication Date:
Mar 01, 1985
Product Type:
Journal Article
Reference Number:
AIX-17-006603; EDB-86-044323
Resource Relation:
Journal Name: Kaku Igaku; (Japan); Journal Volume: 22:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; LUNGS; SCINTISCANNING; RESPIRATORY SYSTEM DISEASES; DIAGNOSIS; TECHNETIUM 99; DIAGNOSTIC USES; AEROSOLS; BIOLOGICAL FUNCTIONS; BREATH; IMAGES; INHALATION; ISOMERIC NUCLEI; REFERENCE MAN; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COLLOIDS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; DISPERSIONS; FUNCTIONS; HOURS LIVING RADIOISOTOPES; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RESPIRATORY SYSTEM; SOLS; TECHNETIUM ISOTOPES; USES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6257705
Research Organizations:
Tokushima Univ., Japan, School of Medicine
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KAIGB
Submitting Site:
HEDB
Size:
Pages: 293-298
Announcement Date:

Journal Article:

Citation Formats

Sui, Osamu, and Shimazu, Hideki. Aerosol lung inhalation scintigraphy in normal subjects. Japan: N. p., 1985. Web.
Sui, Osamu, & Shimazu, Hideki. Aerosol lung inhalation scintigraphy in normal subjects. Japan.
Sui, Osamu, and Shimazu, Hideki. 1985. "Aerosol lung inhalation scintigraphy in normal subjects." Japan.
@misc{etde_6257705,
title = {Aerosol lung inhalation scintigraphy in normal subjects}
author = {Sui, Osamu, and Shimazu, Hideki}
abstractNote = {We previously reported basic and clinical evaluation of aerosol lung inhalation scintigraphy with /sup 99m/Tc-millimicrosphere albumin (milli MISA) and concluded aerosol inhalation scintigraphy with /sup 99m/Tc-milli MISA was useful for routine examination. But central airway deposit of aerosol particles was found in not only the patients with chronic obstructive pulmonary disease (COPD) but also normal subjects. So we performed aerosol inhalation scintigraphy in normal subjects and evaluated their scintigrams. The subjects had normal values of FEVsub(1.0)% (more than 70%) in lung function tests, no abnormal findings in chest X-ray films and no symptoms and signs. The findings of aerosol inhalation scintigrams in them were classified into 3 patterns; type I: homogeneous distribution without central airway deposit, type II: homogeneous distribution with central airway deposit, type III: inhomogeneous distribution. These patterns were compared with lung function tests. There was no significant correlation between type I and type II in lung function tests. Type III was different from type I and type II in inhomogeneous distribution. This finding showed no correlation with %VC, FEVsub(1.0)%, MMF, V radical50 and V radical50/V radical25, but good correlation with V radical25 in a maximum forced expiratory flow-volume curve. Flow-volume curve is one of the sensitive methods in early detection of COPD, so inhomogeneous distribution of type III is considered to be due to small airway dysfunction.}
journal = {Kaku Igaku; (Japan)}
volume = {22:3}
journal type = {AC}
place = {Japan}
year = {1985}
month = {Mar}
}