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Effect of air and water pollutants on human health

Abstract

The two basic approaches in the study of the influence of air and water pollutants on human health are reviewed. The first one is an experimental or toxicological approach, concerned with biochemical, physiological, and clinical lesions, with the mechanism of the genesis of such lesions, and with the possible relations between the toxic dose and the extent or degree of the lesions. Thus, considerable changes in the electrolyte and trace element concentrations in the organism were observed following short-term exposure to such air pollutants as ozone and nitrogen dioxide which cause emphysema in a short time. Rather stable equilibrium between the uptake and excretion of lead was established. The increase in the blood lead level is accompanied by a decrease in the aminolevulinic acid dehydratase activity, a change believed to have no functional consequence. The other, epidemiological, approach is based on the study of human populations actually exposed to pollutants in daily life. Such epidemiological studies are complicated by the large number of extraneous variables playing a significant role in such discrete effects. Epidemiological studies are concerned with the establishment of relationships between specific or nonspecific mortality and morbidity associated with the actual pollution level as compared with control areas  More>>
Authors:
Publication Date:
Jan 01, 1973
Product Type:
Journal Article
Reference Number:
EDB-79-107511
Resource Relation:
Journal Name: J. Pharm. Belg.; (Belgium); Journal Volume: 28:5
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; AIR POLLUTION; HEALTH HAZARDS; TOXICITY; LEAD; NITROGEN DIOXIDE; OZONE; SMOG; ENVIRONMENTAL EFFECTS; WATER POLLUTION; AMINOLEVULINIC ACID; BIOCHEMISTRY; DEHYDROGENASES; DOSE-RESPONSE RELATIONSHIPS; EMPHYSEMA; EPIDEMIOLOGY; ETIOLOGY; EXCRETION; HUMAN POPULATIONS; LOS ANGELES; MORTALITY; PHYSIOLOGY; RESPIRATORY SYSTEM DISEASES; UPTAKE; AMINO ACIDS; CALIFORNIA; CARBOXYLIC ACIDS; CHALCOGENIDES; CHEMISTRY; CLEARANCE; DISEASES; ELEMENTS; ENZYMES; HAZARDS; METALS; NITROGEN COMPOUNDS; NITROGEN OXIDES; NORTH AMERICA; ORGANIC ACIDS; ORGANIC COMPOUNDS; OXIDES; OXIDOREDUCTASES; OXYGEN COMPOUNDS; POLLUTION; POPULATIONS; USA; WESTERN REGION; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987); 551000 - Physiological Systems
OSTI ID:
6251021
Country of Origin:
Belgium
Language:
French
Other Identifying Numbers:
Journal ID: CODEN: JPBEA
Submitting Site:
APA
Size:
Pages: 605-627
Announcement Date:
Sep 01, 1979

Citation Formats

Rhondia, D. Effect of air and water pollutants on human health. Belgium: N. p., 1973. Web.
Rhondia, D. Effect of air and water pollutants on human health. Belgium.
Rhondia, D. 1973. "Effect of air and water pollutants on human health." Belgium.
@misc{etde_6251021,
title = {Effect of air and water pollutants on human health}
author = {Rhondia, D}
abstractNote = {The two basic approaches in the study of the influence of air and water pollutants on human health are reviewed. The first one is an experimental or toxicological approach, concerned with biochemical, physiological, and clinical lesions, with the mechanism of the genesis of such lesions, and with the possible relations between the toxic dose and the extent or degree of the lesions. Thus, considerable changes in the electrolyte and trace element concentrations in the organism were observed following short-term exposure to such air pollutants as ozone and nitrogen dioxide which cause emphysema in a short time. Rather stable equilibrium between the uptake and excretion of lead was established. The increase in the blood lead level is accompanied by a decrease in the aminolevulinic acid dehydratase activity, a change believed to have no functional consequence. The other, epidemiological, approach is based on the study of human populations actually exposed to pollutants in daily life. Such epidemiological studies are complicated by the large number of extraneous variables playing a significant role in such discrete effects. Epidemiological studies are concerned with the establishment of relationships between specific or nonspecific mortality and morbidity associated with the actual pollution level as compared with control areas and control populations. A qualitative relationship between the increasing pollution level and advanced date of death was determinef for populations with respiratory and cardiovascular diseases. A relationship was found between the high pollution level and the number of patients hospitalized during high-pollution in Los Angeles.}
journal = []
volume = {28:5}
journal type = {AC}
place = {Belgium}
year = {1973}
month = {Jan}
}