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Pathogenesis of Granozan (ethylmercury chloride) poisoning in pigs

Abstract

This paper deals with the pathology of mercury poisoning in pigs aged 3-4 months, given daily 2 g Granozan (40 mg ethylmercury chloride) in compounded feed for up to 19 days, and also in pigs of various ages that developed mercury poisoning after consuming grain treated with Granozan. The pigs were killed and examined before the appearance of symptoms and also after acute and chronic mercury poisoning. The onset of mercury poisoning was characterized by anorexia, loss of weight, diarrhea, weakness and paralysis. The organs and tissues of animals killed 1-2 days before the appearance of symptoms (usually on day 14), or dying from mercury poisoning, contained the following amounts of accumulated Hg (mg per 100 g): kidneys 10.35, liver 4.3, muscles 1.36, spleen 1.38, pancreas 0.43, medulla oblongata 0.65, cerebellum 0.79, heart 0.75, mesenteric lymph nodes 0.71, submandibular salivary glands 0.59, stomach wall 0.69, and cecal wall 0.76. In subclinical cases the symptoms and lesions were absent, but the mercury content of organs and tissue was similar to that in animals dying from poisoning, i.e. (mg per 100g): kidneys 10.35, liver 4.3, muscles 1.36, and brain 0.8.
Publication Date:
Jan 01, 1971
Product Type:
Journal Article
Reference Number:
EDB-86-055384
Resource Relation:
Journal Name: Tr. Vses. Inst. Eksp. Vet.; (USSR); Journal Volume: 39
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ORGANIC MERCURY COMPOUNDS; TISSUE DISTRIBUTION; TOXICITY; SWINE; CONTAMINATION; BIOLOGICAL ACCUMULATION; BRAIN; HEART; INGESTION; KIDNEYS; LIVER; LYMPH NODES; MUSCLES; PANCREAS; PATHOGENESIS; SALIVARY GLANDS; SPLEEN; STOMACH; SYMPTOMS; ANIMALS; BODY; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; DIGESTIVE SYSTEM; DISTRIBUTION; DOMESTIC ANIMALS; ENDOCRINE GLANDS; GASTROINTESTINAL TRACT; GLANDS; INTAKE; LYMPHATIC SYSTEM; MAMMALS; MERCURY COMPOUNDS; NERVOUS SYSTEM; ORGANIC COMPOUNDS; ORGANS; VERTEBRATES; 560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
OSTI ID:
6185349
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: TEVVA
Submitting Site:
JMT
Size:
Pages: 331-338
Announcement Date:
Mar 01, 1986

Citation Formats

Ardatova, A N, and Yakusheva, O V. Pathogenesis of Granozan (ethylmercury chloride) poisoning in pigs. USSR: N. p., 1971. Web.
Ardatova, A N, & Yakusheva, O V. Pathogenesis of Granozan (ethylmercury chloride) poisoning in pigs. USSR.
Ardatova, A N, and Yakusheva, O V. 1971. "Pathogenesis of Granozan (ethylmercury chloride) poisoning in pigs." USSR.
@misc{etde_6185349,
title = {Pathogenesis of Granozan (ethylmercury chloride) poisoning in pigs}
author = {Ardatova, A N, and Yakusheva, O V}
abstractNote = {This paper deals with the pathology of mercury poisoning in pigs aged 3-4 months, given daily 2 g Granozan (40 mg ethylmercury chloride) in compounded feed for up to 19 days, and also in pigs of various ages that developed mercury poisoning after consuming grain treated with Granozan. The pigs were killed and examined before the appearance of symptoms and also after acute and chronic mercury poisoning. The onset of mercury poisoning was characterized by anorexia, loss of weight, diarrhea, weakness and paralysis. The organs and tissues of animals killed 1-2 days before the appearance of symptoms (usually on day 14), or dying from mercury poisoning, contained the following amounts of accumulated Hg (mg per 100 g): kidneys 10.35, liver 4.3, muscles 1.36, spleen 1.38, pancreas 0.43, medulla oblongata 0.65, cerebellum 0.79, heart 0.75, mesenteric lymph nodes 0.71, submandibular salivary glands 0.59, stomach wall 0.69, and cecal wall 0.76. In subclinical cases the symptoms and lesions were absent, but the mercury content of organs and tissue was similar to that in animals dying from poisoning, i.e. (mg per 100g): kidneys 10.35, liver 4.3, muscles 1.36, and brain 0.8.}
journal = []
volume = {39}
journal type = {AC}
place = {USSR}
year = {1971}
month = {Jan}
}