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Histological changes in rectum following radiotherapy in cases of carcinoma cervix uteri

Abstract

Rectal biopsy was done in 39 follow-up cases of squamous cell carcinoma of cervix treated with radiotherapy who clinically presented as cases of radiation proctitis. On histological examination, definite evidence of radiation injury was found in 23 cases. In rectal mucosa, radiation ulcers, broken epithelial lining, glandular atrophy, inflammatory cell infiltration, and edema of stroma were seen. Muscularis mucosa was either intact or partially broken. In submucosa, blood vessels showed endarteritis, plasma cell infiltration, fibrinoid necrosis, and hyalinization of vessel wall. In a few cases, hyalinization, edema, and vacuolation of muscle fibres were seen in muscle layer. In one case, squamous cell carcinoma of rectum was diagnosed. During follow-up examinations no complication due to rectal biopsy was observed.
Authors:
Gill, J K; Rohatgi, V K; Lahiri, B; Aggarwal, B M [1] 
  1. S.N. Medical Coll., Agra (India)
Publication Date:
May 01, 1978
Product Type:
Journal Article
Reference Number:
AIX-10-423380; EDB-79-101451
Resource Relation:
Journal Name: Indian J. Radiol.; (India); Journal Volume: 32:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; PROCTITIS; RADIOINDUCTION; RADIOTHERAPY; SIDE EFFECTS; RECTUM; BIOLOGICAL RADIATION EFFECTS; BLOOD VESSELS; CARCINOMAS; EPITHELIUM; FIBROBLASTS; MUCOUS MEMBRANES; MUSCLES; PATIENTS; PHOTOMICROGRAPHY; RADIATION INJURIES; UROGENITAL SYSTEM DISEASES; UTERUS; WOMEN; ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; BODY; CARDIOVASCULAR SYSTEM; CONNECTIVE TISSUE CELLS; DIGESTIVE SYSTEM; DIGESTIVE SYSTEM DISEASES; DISEASES; FEMALE GENITALS; FEMALES; GASTROINTESTINAL TRACT; INJURIES; INTESTINES; LARGE INTESTINE; MAMMALS; MAN; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; PHOTOGRAPHY; PRIMATES; RADIATION EFFECTS; RADIOLOGY; SOMATIC CELLS; THERAPY; TISSUES; VERTEBRATES; 560151* - Radiation Effects on Animals- Man; 550603 - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
6184603
Country of Origin:
India
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: IJRAA
Submitting Site:
INIS
Size:
Pages: 99-102
Announcement Date:
Mar 01, 1979

Citation Formats

Gill, J K, Rohatgi, V K, Lahiri, B, and Aggarwal, B M. Histological changes in rectum following radiotherapy in cases of carcinoma cervix uteri. India: N. p., 1978. Web.
Gill, J K, Rohatgi, V K, Lahiri, B, & Aggarwal, B M. Histological changes in rectum following radiotherapy in cases of carcinoma cervix uteri. India.
Gill, J K, Rohatgi, V K, Lahiri, B, and Aggarwal, B M. 1978. "Histological changes in rectum following radiotherapy in cases of carcinoma cervix uteri." India.
@misc{etde_6184603,
title = {Histological changes in rectum following radiotherapy in cases of carcinoma cervix uteri}
author = {Gill, J K, Rohatgi, V K, Lahiri, B, and Aggarwal, B M}
abstractNote = {Rectal biopsy was done in 39 follow-up cases of squamous cell carcinoma of cervix treated with radiotherapy who clinically presented as cases of radiation proctitis. On histological examination, definite evidence of radiation injury was found in 23 cases. In rectal mucosa, radiation ulcers, broken epithelial lining, glandular atrophy, inflammatory cell infiltration, and edema of stroma were seen. Muscularis mucosa was either intact or partially broken. In submucosa, blood vessels showed endarteritis, plasma cell infiltration, fibrinoid necrosis, and hyalinization of vessel wall. In a few cases, hyalinization, edema, and vacuolation of muscle fibres were seen in muscle layer. In one case, squamous cell carcinoma of rectum was diagnosed. During follow-up examinations no complication due to rectal biopsy was observed.}
journal = []
volume = {32:2}
journal type = {AC}
place = {India}
year = {1978}
month = {May}
}