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Elimination of radioactivity after intratracheal instillation of tritiated 3, 4-benzopyrene in hamsters

Journal Article:

Abstract

Injection and recovery experiments of tritiated 3,4-benzopyrene (BaP) injected alone or with particulate carriers into hamsters were performed. After 21 days, asbestos or carbon black carriers had significantly increased the retention of BaP in the lung. Elimination was rapid at first (2 weeks: and little influenced by carrier; slower rate of elimination was noted after that. Carriers increased recoverable macrophages but decreased the amount of radioactivity per macrophage. Radioactivity was similar in all groups for kidney, liver, blood, feces, and urine.
Publication Date:
Jan 01, 1969
Product Type:
Journal Article
Reference Number:
EDB-79-075526
Resource Relation:
Journal Name: Br. J. Cancer; (United Kingdom); Journal Volume: 23
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; BENZOPYRENE; BIOLOGICAL EFFECTS; RETENTION; POLYCYCLIC AROMATIC HYDROCARBONS; EXCRETION; AIR POLLUTION; ASBESTOS; BLOOD; CARBON BLACK; CARRIERS; FECES; HAMSTERS; INTRATRACHEAL ADMINISTRATION; KIDNEYS; LIVER; LUNGS; MACROPHAGES; RADIOACTIVITY; URINE; ANIMAL CELLS; ANIMALS; AROMATICS; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY; BODY FLUIDS; CARBON; CLEARANCE; CONDENSED AROMATICS; CONNECTIVE TISSUE CELLS; DIGESTIVE SYSTEM; ELEMENTS; GLANDS; HYDROCARBONS; MAMMALS; NONMETALS; ORGANIC COMPOUNDS; ORGANS; PHAGOCYTES; POLLUTION; RESPIRATORY SYSTEM; RODENTS; SOMATIC CELLS; VERTEBRATES; WASTES; 560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987); 550500 - Metabolism
OSTI ID:
6179245
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: BJCAA
Submitting Site:
TIC
Size:
Pages: 103-115
Announcement Date:

Journal Article:

Citation Formats

Pylev, L N, Roe, F J.C., and Warwick, G P. Elimination of radioactivity after intratracheal instillation of tritiated 3, 4-benzopyrene in hamsters. United Kingdom: N. p., 1969. Web.
Pylev, L N, Roe, F J.C., & Warwick, G P. Elimination of radioactivity after intratracheal instillation of tritiated 3, 4-benzopyrene in hamsters. United Kingdom.
Pylev, L N, Roe, F J.C., and Warwick, G P. 1969. "Elimination of radioactivity after intratracheal instillation of tritiated 3, 4-benzopyrene in hamsters." United Kingdom.
@misc{etde_6179245,
title = {Elimination of radioactivity after intratracheal instillation of tritiated 3, 4-benzopyrene in hamsters}
author = {Pylev, L N, Roe, F J.C., and Warwick, G P}
abstractNote = {Injection and recovery experiments of tritiated 3,4-benzopyrene (BaP) injected alone or with particulate carriers into hamsters were performed. After 21 days, asbestos or carbon black carriers had significantly increased the retention of BaP in the lung. Elimination was rapid at first (2 weeks: and little influenced by carrier; slower rate of elimination was noted after that. Carriers increased recoverable macrophages but decreased the amount of radioactivity per macrophage. Radioactivity was similar in all groups for kidney, liver, blood, feces, and urine.}
journal = {Br. J. Cancer; (United Kingdom)}
volume = {23}
journal type = {AC}
place = {United Kingdom}
year = {1969}
month = {Jan}
}