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Serotonergic synaptic input to facial motoneurons: localization by electron-microscopic autoradiography

Abstract

Serotonergic nerve terminals in the facial motor nucleus were labelled with (/sup 3/H)5-hydroxytryptamine. When serotonergic nerve terminals were destroyed (by the selective neurotoxin 5,7-dihydroxytryptamine) the labelling was lost. By electron-microscopic autoradiography, labelled serotonergic terminals were found to make axo-dendritic or axo-somatic junctions with facial motor neurons. No axo-axonic junctions were observed. These morphological findings are consistent with physiological studies which indicate that 5-hydroxytryptamine facilitates the excitation of facial motoneurons through a direct postsynaptic action.
Authors:
Aghajanian, G K; McCall, R B [1] 
  1. Yale Univ., New Haven, CT (USA). School of Medicine
Publication Date:
Dec 01, 1980
Product Type:
Journal Article
Reference Number:
AIX-12-610067; EDB-81-131899
Resource Relation:
Journal Name: Neuroscience; (United Kingdom); Journal Volume: 5:12
Subject:
59 BASIC BIOLOGICAL SCIENCES; NERVE CELLS; AUTORADIOGRAPHY; RECEPTORS; MORPHOLOGY; FACE; HYDROXY COMPOUNDS; LABELLED COMPOUNDS; MORPHOLOGICAL CHANGES; TRITIUM; TRYPTAMINES; AMINES; ANIMAL CELLS; AZOLES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; BODY AREAS; HEAD; HETEROCYCLIC COMPOUNDS; HYDROGEN ISOTOPES; INDOLES; ISOTOPES; LIGHT NUCLEI; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PYRROLES; RADIOISOTOPES; SOMATIC CELLS; YEARS LIVING RADIOISOTOPES; 550801* - Morphology- Tracer Techniques
OSTI ID:
6172389
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: NRSCD
Submitting Site:
INIS
Size:
Pages: 2155-2162
Announcement Date:
Jul 01, 1981

Citation Formats

Aghajanian, G K, and McCall, R B. Serotonergic synaptic input to facial motoneurons: localization by electron-microscopic autoradiography. United Kingdom: N. p., 1980. Web. doi:10.1016/0306-4522(80)90132-3.
Aghajanian, G K, & McCall, R B. Serotonergic synaptic input to facial motoneurons: localization by electron-microscopic autoradiography. United Kingdom. https://doi.org/10.1016/0306-4522(80)90132-3
Aghajanian, G K, and McCall, R B. 1980. "Serotonergic synaptic input to facial motoneurons: localization by electron-microscopic autoradiography." United Kingdom. https://doi.org/10.1016/0306-4522(80)90132-3.
@misc{etde_6172389,
title = {Serotonergic synaptic input to facial motoneurons: localization by electron-microscopic autoradiography}
author = {Aghajanian, G K, and McCall, R B}
abstractNote = {Serotonergic nerve terminals in the facial motor nucleus were labelled with (/sup 3/H)5-hydroxytryptamine. When serotonergic nerve terminals were destroyed (by the selective neurotoxin 5,7-dihydroxytryptamine) the labelling was lost. By electron-microscopic autoradiography, labelled serotonergic terminals were found to make axo-dendritic or axo-somatic junctions with facial motor neurons. No axo-axonic junctions were observed. These morphological findings are consistent with physiological studies which indicate that 5-hydroxytryptamine facilitates the excitation of facial motoneurons through a direct postsynaptic action.}
doi = {10.1016/0306-4522(80)90132-3}
journal = []
volume = {5:12}
journal type = {AC}
place = {United Kingdom}
year = {1980}
month = {Dec}
}