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Evaluation of T-lymphocyte populations in humans exposed to action of beryllium compounds

Journal Article:

Abstract

Earlier studies in vitro on beryllosis and cellular immunity, and knowledge of the role of T-cells in development of cellular immunity suggested usefulness of a quantitative determination of T-cell populations in beryllosis. Assay was based on the test for spontaneous rosette formation in beryllosis patients and in healthy workers who come in contact with Be compounds (Jondal, modified by M. A. Stenina) and on the leucocyte migration inhibition reaction (Soborg and Bendixen). A large range of changes were revealed in population size and in adhesion qualities of T-lymphocytes in the patients and in those exposed to Be. The test for spontaneous rosette formation was found to be sufficiently indicative for use in study of beryllosis pathogenesis and to correlate with the state of activity of the disease.
Authors:
Publication Date:
Oct 01, 1977
Product Type:
Journal Article
Reference Number:
EDB-79-065336
Resource Relation:
Journal Name: Gig. Tr. Prof. Zabol.; (USSR); Journal Volume: 10
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE; 59 BASIC BIOLOGICAL SCIENCES; BERYLLIUM COMPOUNDS; BIOLOGICAL EFFECTS; LYMPHOCYTES; COMPARATIVE EVALUATIONS; BERYLLIOSIS; BLOOD CELLS; DISEASES; HUMAN POPULATIONS; IMMUNITY; INHIBITION; LEUKOCYTES; LYMPHATIC SYSTEM; OCCUPATIONAL DISEASES; PATHOGENESIS; PATIENTS; ALKALINE EARTH METAL COMPOUNDS; ANIMAL CELLS; BIOLOGICAL MATERIALS; BLOOD; BODY FLUIDS; CONNECTIVE TISSUE CELLS; PNEUMOCONIOSES; POPULATIONS; RESPIRATORY SYSTEM DISEASES; SOMATIC CELLS; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987); 552000 - Public Health; 550900 - Pathology
OSTI ID:
6163382
Research Organizations:
Inst. of Labor Hygiene and Occupational Diseases, Moscow, USSR
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: GTPZA
Submitting Site:
HEDB
Size:
Pages: 52-54
Announcement Date:

Journal Article:

Citation Formats

Ermakova, N G. Evaluation of T-lymphocyte populations in humans exposed to action of beryllium compounds. USSR: N. p., 1977. Web.
Ermakova, N G. Evaluation of T-lymphocyte populations in humans exposed to action of beryllium compounds. USSR.
Ermakova, N G. 1977. "Evaluation of T-lymphocyte populations in humans exposed to action of beryllium compounds." USSR.
@misc{etde_6163382,
title = {Evaluation of T-lymphocyte populations in humans exposed to action of beryllium compounds}
author = {Ermakova, N G}
abstractNote = {Earlier studies in vitro on beryllosis and cellular immunity, and knowledge of the role of T-cells in development of cellular immunity suggested usefulness of a quantitative determination of T-cell populations in beryllosis. Assay was based on the test for spontaneous rosette formation in beryllosis patients and in healthy workers who come in contact with Be compounds (Jondal, modified by M. A. Stenina) and on the leucocyte migration inhibition reaction (Soborg and Bendixen). A large range of changes were revealed in population size and in adhesion qualities of T-lymphocytes in the patients and in those exposed to Be. The test for spontaneous rosette formation was found to be sufficiently indicative for use in study of beryllosis pathogenesis and to correlate with the state of activity of the disease.}
journal = {Gig. Tr. Prof. Zabol.; (USSR)}
volume = {10}
journal type = {AC}
place = {USSR}
year = {1977}
month = {Oct}
}