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Evaluation of the efficacy of palliative irradiation with high fractionated doses and planned intervals of patients with advanced cancer of the oral cavity and pharynx. Ocena skutecznosci paliatywnego napromieniania wysokimi dawkami frakcyjnymi z planowanymi przerwami chorych na zaawansowanego raka jamy ustnej i gardla

Journal Article:

Abstract

200 patients, previously not treated, with advanced highly differentiated cancer of the oral cavity and pharynx have been palliatively irradiated in the Oncology Center in Cracow in the years 1976-1985. Megavoltage irradiation with fractionated doses 4-5 Gy up to the dose of 20 Gy to the tumor with 4-5 fractions during 4-7 days has been applied. 64 patients received 20 Gy as simple dose, in 65 cases such dose has been repeated after month. 71 patients have been irradiated for the third time with similar dose after another 1 month interval. Partial regression of 25-50% of the tumor volume has been obtained after the first series of irradiation in 19% of patients and more than 50% in 28% of patients, complete regression in 4% of patients. 15,5% of the total number of patients survived 1 year since the initiation of the irradiation, 5% without symptoms of the neoplasm. Worse prognosis is connected with major advancement of the tumor (T{sub 4}, N{sub 2}), poor general condition, cachexia and alcohol addition. Absence of improvement after the first series of irradiations indicates the non-effectiveness of the treatment. Palliative treatment by irradiation with high fractionated doses and planned interval is a safe and efficacious  More>>
Authors:
Skolyszewski, J; Reinfuss, M [1] 
  1. Instytut Onkologii, Cracow (Poland)
Publication Date:
Jan 01, 1988
Product Type:
Journal Article
Reference Number:
AIX-23-001673; EDB-92-007342
Resource Relation:
Journal Name: Nowotwory; (Poland); Journal Volume: 38:4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ORAL CAVITY; FRACTIONATED IRRADIATION; PHARYNX; CARCINOMAS; EFFICIENCY; PATIENTS; RADIATION DOSES; RADIOTHERAPY; STATISTICAL DATA; SURVIVAL CURVES; BODY; DATA; DIGESTIVE SYSTEM; DISEASES; DOSES; INFORMATION; IRRADIATION; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; NUMERICAL DATA; ORGANS; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY; 550603* - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
6142249
Country of Origin:
Poland
Language:
Polish
Other Identifying Numbers:
Journal ID: ISSN 0029-540X; CODEN: NOWOA
Submitting Site:
INIS
Size:
Pages: 251-260
Announcement Date:

Journal Article:

Citation Formats

Skolyszewski, J, and Reinfuss, M. Evaluation of the efficacy of palliative irradiation with high fractionated doses and planned intervals of patients with advanced cancer of the oral cavity and pharynx. Ocena skutecznosci paliatywnego napromieniania wysokimi dawkami frakcyjnymi z planowanymi przerwami chorych na zaawansowanego raka jamy ustnej i gardla. Poland: N. p., 1988. Web.
Skolyszewski, J, & Reinfuss, M. Evaluation of the efficacy of palliative irradiation with high fractionated doses and planned intervals of patients with advanced cancer of the oral cavity and pharynx. Ocena skutecznosci paliatywnego napromieniania wysokimi dawkami frakcyjnymi z planowanymi przerwami chorych na zaawansowanego raka jamy ustnej i gardla. Poland.
Skolyszewski, J, and Reinfuss, M. 1988. "Evaluation of the efficacy of palliative irradiation with high fractionated doses and planned intervals of patients with advanced cancer of the oral cavity and pharynx. Ocena skutecznosci paliatywnego napromieniania wysokimi dawkami frakcyjnymi z planowanymi przerwami chorych na zaawansowanego raka jamy ustnej i gardla." Poland.
@misc{etde_6142249,
title = {Evaluation of the efficacy of palliative irradiation with high fractionated doses and planned intervals of patients with advanced cancer of the oral cavity and pharynx. Ocena skutecznosci paliatywnego napromieniania wysokimi dawkami frakcyjnymi z planowanymi przerwami chorych na zaawansowanego raka jamy ustnej i gardla}
author = {Skolyszewski, J, and Reinfuss, M}
abstractNote = {200 patients, previously not treated, with advanced highly differentiated cancer of the oral cavity and pharynx have been palliatively irradiated in the Oncology Center in Cracow in the years 1976-1985. Megavoltage irradiation with fractionated doses 4-5 Gy up to the dose of 20 Gy to the tumor with 4-5 fractions during 4-7 days has been applied. 64 patients received 20 Gy as simple dose, in 65 cases such dose has been repeated after month. 71 patients have been irradiated for the third time with similar dose after another 1 month interval. Partial regression of 25-50% of the tumor volume has been obtained after the first series of irradiation in 19% of patients and more than 50% in 28% of patients, complete regression in 4% of patients. 15,5% of the total number of patients survived 1 year since the initiation of the irradiation, 5% without symptoms of the neoplasm. Worse prognosis is connected with major advancement of the tumor (T{sub 4}, N{sub 2}), poor general condition, cachexia and alcohol addition. Absence of improvement after the first series of irradiations indicates the non-effectiveness of the treatment. Palliative treatment by irradiation with high fractionated doses and planned interval is a safe and efficacious method. 1 fig., 6 tabs., 14 refs. (author).}
journal = {Nowotwory; (Poland)}
volume = {38:4}
journal type = {AC}
place = {Poland}
year = {1988}
month = {Jan}
}