You need JavaScript to view this

HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt

Journal Article:

Abstract

In a skin investigation of 853 individuals working with hard metal manufacturing 39 cases of cobalt allergy were found. Thirty-five of the individuals with cobalt sensitivity and 102 matched controls were HLA-A, -B, -C and -DR typed. No significantly deviating HLA antigen frequencies were observed when the two groups were compared. Thus, there are no signs that a certain HLA antigen would dispose to cobalt allergy. In the cobalt sensitive group the B7 positive individuals showed particularly often simultaneous reactions to other contact allergens. The B12 positive individuals had low reactivity while the A28 positive showed high reactivity.
Publication Date:
Jan 01, 1984
Product Type:
Journal Article
Reference Number:
EDB-85-015894
Resource Relation:
Journal Name: Acta Derm.-Venereol.; (Sweden); Journal Volume: 64:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ANTIGENS; IMMUNE REACTIONS; COBALT; BIOLOGICAL EFFECTS; ALLERGY; DERMATITIS; PERSONNEL; SKIN; BODY; DISEASES; ELEMENTS; METALS; ORGANS; PATHOLOGICAL CHANGES; SKIN DISEASES; TRANSITION ELEMENTS; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
OSTI ID:
6128465
Research Organizations:
Univ. Hospital, Uppsala, Sweden
Country of Origin:
Sweden
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: ADVEA
Submitting Site:
HEDB
Size:
Pages: 121-124
Announcement Date:

Journal Article:

Citation Formats

Fischer, T, Rystedt, I, Saefwenberg, J, and Egle, I. HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt. Sweden: N. p., 1984. Web.
Fischer, T, Rystedt, I, Saefwenberg, J, & Egle, I. HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt. Sweden.
Fischer, T, Rystedt, I, Saefwenberg, J, and Egle, I. 1984. "HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt." Sweden.
@misc{etde_6128465,
title = {HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt}
author = {Fischer, T, Rystedt, I, Saefwenberg, J, and Egle, I}
abstractNote = {In a skin investigation of 853 individuals working with hard metal manufacturing 39 cases of cobalt allergy were found. Thirty-five of the individuals with cobalt sensitivity and 102 matched controls were HLA-A, -B, -C and -DR typed. No significantly deviating HLA antigen frequencies were observed when the two groups were compared. Thus, there are no signs that a certain HLA antigen would dispose to cobalt allergy. In the cobalt sensitive group the B7 positive individuals showed particularly often simultaneous reactions to other contact allergens. The B12 positive individuals had low reactivity while the A28 positive showed high reactivity.}
journal = {Acta Derm.-Venereol.; (Sweden)}
volume = {64:2}
journal type = {AC}
place = {Sweden}
year = {1984}
month = {Jan}
}