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Radioimmunoassay of serum myoglobin in neuromuscular diseases

Journal Article:

Abstract

Radioimmunoassay of serum myoglobin was performed in 85 patients with muscular symptoms. Elevated levels were found in 93% of patients with myogenic myopathy, in 54% with myasthenia gravis and in 50% with neurogenic myopathy. All 11 patients with polymyositis had elevated myoglobin concentrations. In six of seven patients with polymyositis, who were followed up with repeated determinations, a clear relationship between myoglobin levels and clinical course was found. In general serum myoglobin seemed to be a more sensitive indicator of muscle disease than creatine kinase.
Authors:
Askmark, H; Osterman, P O; Roxin, L E; Venge, P [1] 
  1. University Hospital, Uppsala (Sweden)
Publication Date:
Jan 01, 1981
Product Type:
Journal Article
Reference Number:
AIX-12-619137; EDB-82-004875
Resource Relation:
Journal Name: J. Neurol., Neurosurg., Psychiatr.; (United Kingdom); Journal Volume: 44:1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MYOGLOBIN; RADIOIMMUNOASSAY; NERVOUS SYSTEM DISEASES; DIAGNOSTIC TECHNIQUES; MUSCLES; CARBOXYLIC ACIDS; DISEASES; GLOBIN; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; ISOTOPE APPLICATIONS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PIGMENTS; PORPHYRINS; PROTEINS; RADIOASSAY; TRACER TECHNIQUES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6113084
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JNNPA
Submitting Site:
INIS
Size:
Pages: 68-72
Announcement Date:
Aug 01, 1981

Journal Article:

Citation Formats

Askmark, H, Osterman, P O, Roxin, L E, and Venge, P. Radioimmunoassay of serum myoglobin in neuromuscular diseases. United Kingdom: N. p., 1981. Web.
Askmark, H, Osterman, P O, Roxin, L E, & Venge, P. Radioimmunoassay of serum myoglobin in neuromuscular diseases. United Kingdom.
Askmark, H, Osterman, P O, Roxin, L E, and Venge, P. 1981. "Radioimmunoassay of serum myoglobin in neuromuscular diseases." United Kingdom.
@misc{etde_6113084,
title = {Radioimmunoassay of serum myoglobin in neuromuscular diseases}
author = {Askmark, H, Osterman, P O, Roxin, L E, and Venge, P}
abstractNote = {Radioimmunoassay of serum myoglobin was performed in 85 patients with muscular symptoms. Elevated levels were found in 93% of patients with myogenic myopathy, in 54% with myasthenia gravis and in 50% with neurogenic myopathy. All 11 patients with polymyositis had elevated myoglobin concentrations. In six of seven patients with polymyositis, who were followed up with repeated determinations, a clear relationship between myoglobin levels and clinical course was found. In general serum myoglobin seemed to be a more sensitive indicator of muscle disease than creatine kinase.}
journal = {J. Neurol., Neurosurg., Psychiatr.; (United Kingdom)}
volume = {44:1}
journal type = {AC}
place = {United Kingdom}
year = {1981}
month = {Jan}
}