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Renal scintigraphy with captopril for the investigation of arterial hypertension. Captopril-Nierenfunktionsszintigraphie (C-NFSZ) bei der Abklaerung der arteriellen Hypertonie

Abstract

Renal artery stenosis (RAS) is a rare cause of hypertension. Radiological tests can disclose the morphological changes, but not their functional effect on renal function and perfusion. Normalization of the blood pressure can be achieved by intervention (operation, percutaneous transluminal renal angiography; PTRA), in cases of prolonged RAS-induced hypertension long-term preservation of the organ function is most important. The purpose of this study was the validation of captopril renography as a screening test for hypertension secondary to RAS prior to PTRA. Captopril renography with {sup 99m}Tc-MAG 3 has a high sensitivity (94%) and acceptable specificity (88%) for the screening of hypertensive patients. The positive predictive value is 74% and the negative predictive value 98%, compared with the 'gold standard' of angiography. (orig.).
Authors:
Nitzsche, E; Strauss, E; Moser, E; [1]  Grosser, G; [2]  Rump, C; Keller, E; [3]  Meyer, E [4] 
  1. Freiburg Univ. (Germany, F.R.). Abt. Klinische Nuklearmedizin
  2. Freiburg Univ. (Germany, F.R.). Abt. Roentgendiagnostik Sankt Marienkrankenhaus, Frankfurt am Main (Germany, F.R.). Radiologische Abt.
  3. Freiburg Univ. (Germany, F.R.). Abt. Nephrologie
  4. Freiburg Univ. (Germany, F.R.). Abt. Roentgendiagnostik
Publication Date:
Mar 01, 1991
Product Type:
Journal Article
Reference Number:
DEN-91-002680; EDB-91-053626
Resource Relation:
Journal Name: Radiologe; (Germany, F.R.); Journal Volume: 31:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DYNAMIC FUNCTION STUDIES; SCINTISCANNING; KIDNEYS; BLOOD FLOW; HYPERTENSION; BIOMEDICAL RADIOGRAPHY; DIAGNOSIS; GLYCINE; IMAGES; ISOMERIC NUCLEI; PATIENTS; RADIOPHARMACEUTICALS; SENSITIVITY; SPECIFICITY; TECHNETIUM 99; TECHNETIUM COMPLEXES; UROGENITAL SYSTEM DISEASES; VASCULAR DISEASES; X-RAY RADIOGRAPHY; AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CARDIOVASCULAR DISEASES; COMPLEXES; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; HOURS LIVING RADIOISOTOPES; INDUSTRIAL RADIOGRAPHY; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MEDICINE; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RADIOLOGY; SYMPTOMS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPLEXES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550602 - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
6101447
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: ISSN 0033-832X; CODEN: RDLGB
Submitting Site:
DEN
Size:
Pages: 141-146
Announcement Date:
May 01, 1991

Citation Formats

Nitzsche, E, Strauss, E, Moser, E, Grosser, G, Rump, C, Keller, E, and Meyer, E. Renal scintigraphy with captopril for the investigation of arterial hypertension. Captopril-Nierenfunktionsszintigraphie (C-NFSZ) bei der Abklaerung der arteriellen Hypertonie. Germany: N. p., 1991. Web.
Nitzsche, E, Strauss, E, Moser, E, Grosser, G, Rump, C, Keller, E, & Meyer, E. Renal scintigraphy with captopril for the investigation of arterial hypertension. Captopril-Nierenfunktionsszintigraphie (C-NFSZ) bei der Abklaerung der arteriellen Hypertonie. Germany.
Nitzsche, E, Strauss, E, Moser, E, Grosser, G, Rump, C, Keller, E, and Meyer, E. 1991. "Renal scintigraphy with captopril for the investigation of arterial hypertension. Captopril-Nierenfunktionsszintigraphie (C-NFSZ) bei der Abklaerung der arteriellen Hypertonie." Germany.
@misc{etde_6101447,
title = {Renal scintigraphy with captopril for the investigation of arterial hypertension. Captopril-Nierenfunktionsszintigraphie (C-NFSZ) bei der Abklaerung der arteriellen Hypertonie}
author = {Nitzsche, E, Strauss, E, Moser, E, Grosser, G, Rump, C, Keller, E, and Meyer, E}
abstractNote = {Renal artery stenosis (RAS) is a rare cause of hypertension. Radiological tests can disclose the morphological changes, but not their functional effect on renal function and perfusion. Normalization of the blood pressure can be achieved by intervention (operation, percutaneous transluminal renal angiography; PTRA), in cases of prolonged RAS-induced hypertension long-term preservation of the organ function is most important. The purpose of this study was the validation of captopril renography as a screening test for hypertension secondary to RAS prior to PTRA. Captopril renography with {sup 99m}Tc-MAG 3 has a high sensitivity (94%) and acceptable specificity (88%) for the screening of hypertensive patients. The positive predictive value is 74% and the negative predictive value 98%, compared with the 'gold standard' of angiography. (orig.).}
journal = []
volume = {31:3}
journal type = {AC}
place = {Germany}
year = {1991}
month = {Mar}
}