You need JavaScript to view this

Clinical study on eating disorders. Brain atrophy revealed by cranial computed tomography scans

Journal Article:

Abstract

Cranial computed tomography (CT) scans were reviewed in 34 patients with anorexia nervosa (Group I) and 22 with bulimia (Group II) to elucidate the cause and pathological significance of morphological brain alterations. The findings were compared with those from 47 normal women. The incidence of brain atrophy was significantly higher in Group I (17/34, 50%) and Group II (11/22, 50%) than the control group (3/47, 6%). In Group I, there was a significant increase in the left septum-caudate distance, the maximum width of interhemispheric fissure, the width of the both-side Sylvian fissures adjacent to the skull, and the maximum width of the third ventricle. A significant increase in the maximum width of interhemispheric fissure and the width of the left-side Sylvian fissure adjacent to the skull were noted as well in Group II. Ventricular brain ratios were significantly higher in Groups I and II than the control group (6.76 and 7.29 vs 4.55). Brain atrophy did not correlate with age, body weight, malnutrition, eating behavior, depression, thyroid function, EEG findings, or intelligence scale. In Group I, serum cortisol levels after the administration of dexamethasone were correlated with ventricular brain ratio. (Namekawa, K) 51 refs.
Publication Date:
Jun 01, 1988
Product Type:
Journal Article
Reference Number:
JPN-89-009524; EDB-89-103449
Resource Relation:
Journal Name: Osaka-Shi Igakkai Zasshi; (Japan); Journal Volume: 37:2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CEREBRUM; ATROPHY; COMPUTERIZED TOMOGRAPHY; MENTAL DISORDERS; DIAGNOSIS; ANOREXIA; BEHAVIOR; DIET; HYDROCORTISONE; IMAGES; INGESTION; MORPHOLOGICAL CHANGES; PATIENTS; WOMEN; ADRENAL HORMONES; ANIMALS; BODY; BRAIN; CENTRAL NERVOUS SYSTEM; CORTICOSTEROIDS; DIAGNOSTIC TECHNIQUES; FEMALES; GLUCOCORTICOIDS; HYDROXY COMPOUNDS; INTAKE; KETONES; MAMMALS; MAN; NERVOUS SYSTEM; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; PREGNANES; PRIMATES; STEROIDS; TOMOGRAPHY; VERTEBRATES; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
6071776
Research Organizations:
Osaka City Univ. (Japan). Faculty of Medicine
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: OIGZD
Submitting Site:
JPN
Size:
Pages: 385-404
Announcement Date:

Journal Article:

Citation Formats

Nishiwaki, Shinichi. Clinical study on eating disorders. Brain atrophy revealed by cranial computed tomography scans. Japan: N. p., 1988. Web.
Nishiwaki, Shinichi. Clinical study on eating disorders. Brain atrophy revealed by cranial computed tomography scans. Japan.
Nishiwaki, Shinichi. 1988. "Clinical study on eating disorders. Brain atrophy revealed by cranial computed tomography scans." Japan.
@misc{etde_6071776,
title = {Clinical study on eating disorders. Brain atrophy revealed by cranial computed tomography scans}
author = {Nishiwaki, Shinichi}
abstractNote = {Cranial computed tomography (CT) scans were reviewed in 34 patients with anorexia nervosa (Group I) and 22 with bulimia (Group II) to elucidate the cause and pathological significance of morphological brain alterations. The findings were compared with those from 47 normal women. The incidence of brain atrophy was significantly higher in Group I (17/34, 50%) and Group II (11/22, 50%) than the control group (3/47, 6%). In Group I, there was a significant increase in the left septum-caudate distance, the maximum width of interhemispheric fissure, the width of the both-side Sylvian fissures adjacent to the skull, and the maximum width of the third ventricle. A significant increase in the maximum width of interhemispheric fissure and the width of the left-side Sylvian fissure adjacent to the skull were noted as well in Group II. Ventricular brain ratios were significantly higher in Groups I and II than the control group (6.76 and 7.29 vs 4.55). Brain atrophy did not correlate with age, body weight, malnutrition, eating behavior, depression, thyroid function, EEG findings, or intelligence scale. In Group I, serum cortisol levels after the administration of dexamethasone were correlated with ventricular brain ratio. (Namekawa, K) 51 refs.}
journal = {Osaka-Shi Igakkai Zasshi; (Japan)}
volume = {37:2}
journal type = {AC}
place = {Japan}
year = {1988}
month = {Jun}
}