Abstract
A comparison was made between cord blood lymphocytes, normal adult lymphocytes and leukemic cells after membrane iodination with lactoperoxidase. A double-labeling technique using lactoperoxidase iodination with /sup 125/I and /sup 131/I followed by analysis on polyacrylamide gel electrophoresis revealed a number of membrane differences between leukemic, normal and fetal cells. There was a reduction in the 70,000 molecular weight component in cord blood cells compared to adult lymphocytes, and an increase in membrane peptides with molecular weights of 35,000, 20,000, 9,000 and 4,000. Although smaller molecular weight peptides were also present in chronic lymphatic leukemia as well as acute myeloid leukemia, these were shown to be distinct from fetal type membrane components.
Kannourakis, G;
Cauchi, M N
[1]
- Department of Pathology and Immunology, Monash Medical School, Melbourne, Australia
Citation Formats
Kannourakis, G, and Cauchi, M N.
Studies by radioiodination of normal adult, fetal and leukemic cell membranes.
Denmark: N. p.,
1978.
Web.
Kannourakis, G, & Cauchi, M N.
Studies by radioiodination of normal adult, fetal and leukemic cell membranes.
Denmark.
Kannourakis, G, and Cauchi, M N.
1978.
"Studies by radioiodination of normal adult, fetal and leukemic cell membranes."
Denmark.
@misc{etde_6045424,
title = {Studies by radioiodination of normal adult, fetal and leukemic cell membranes}
author = {Kannourakis, G, and Cauchi, M N}
abstractNote = {A comparison was made between cord blood lymphocytes, normal adult lymphocytes and leukemic cells after membrane iodination with lactoperoxidase. A double-labeling technique using lactoperoxidase iodination with /sup 125/I and /sup 131/I followed by analysis on polyacrylamide gel electrophoresis revealed a number of membrane differences between leukemic, normal and fetal cells. There was a reduction in the 70,000 molecular weight component in cord blood cells compared to adult lymphocytes, and an increase in membrane peptides with molecular weights of 35,000, 20,000, 9,000 and 4,000. Although smaller molecular weight peptides were also present in chronic lymphatic leukemia as well as acute myeloid leukemia, these were shown to be distinct from fetal type membrane components.}
journal = []
volume = {6}
journal type = {AC}
place = {Denmark}
year = {1978}
month = {Jan}
}
title = {Studies by radioiodination of normal adult, fetal and leukemic cell membranes}
author = {Kannourakis, G, and Cauchi, M N}
abstractNote = {A comparison was made between cord blood lymphocytes, normal adult lymphocytes and leukemic cells after membrane iodination with lactoperoxidase. A double-labeling technique using lactoperoxidase iodination with /sup 125/I and /sup 131/I followed by analysis on polyacrylamide gel electrophoresis revealed a number of membrane differences between leukemic, normal and fetal cells. There was a reduction in the 70,000 molecular weight component in cord blood cells compared to adult lymphocytes, and an increase in membrane peptides with molecular weights of 35,000, 20,000, 9,000 and 4,000. Although smaller molecular weight peptides were also present in chronic lymphatic leukemia as well as acute myeloid leukemia, these were shown to be distinct from fetal type membrane components.}
journal = []
volume = {6}
journal type = {AC}
place = {Denmark}
year = {1978}
month = {Jan}
}