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Clinical applications of HPLC-competitive protein binding assay for serum 25-hydroxyvitamin D

Journal Article:

Abstract

This report describes the clinical applications of HPLC-competitive protein binding assay for serum 25(OH) Vit D in 156 cases. Serum 25(OH) Vit D of normal human was 33.1 +- 14.8 nmol/L (13.2 +- 5.9 ng/ml), while for various diseases are as follows: rickets, 18.0 +- 9.0 nmol/L (7.2 +- 3.6 ng/ml, n = 36, P < 0.005); hypervitaminosis D, 116.8 +- 31.3 nmol/L (46.7 +- 12.3 ng/ml, n = 6, P < 0.001); renal diseases of children, 25.3 +- 7.3 nmol/L (10.1 +- 2.9 ng/ml, n = 9. P > 0.1); pneumonia of children, 33.8 +- 14.8 nmol/L (13.5 +- 5.9 ng/ml, n = 10, P > 0.5); cirrhosis, 13.8 +- 11.3 nmol/L (5.5 +- 4.5 ng/ml, n = 9, P < 0.001); vasculitis, 25.5 +- 15.3 nmol/L (10.2 +- 6.1 ng/ml, n = 5, P > 0.2); administration of anticonvulsant (1 to 15 years), 19.0 +- 6.5 nmol/L (7.6 +- 2.6 ng/ml, n = 19, P < 0.001); administration of glococorticoids (> 6 months), 15.3 +- 5.0 nmol/L (6.1 +- 2.0 ng/ml, n = 6, P < 0.005); hyperthyroidism, 34.0 +- 23.5 nmol/L (13.6 +- 9.4 ng/ml, n = 13, P > 0.5); pregnant women, 39.8 +- 16.5 nmol/L  More>>
Authors:
Shouli, Yang [1] 
  1. China-Japan Friendship Hospital, Beijing, BJ (China). Inst. of Clinical Medical Science; and others
Publication Date:
Aug 01, 1989
Product Type:
Journal Article
Reference Number:
AIX-22-019204; EDB-91-029362
Resource Relation:
Journal Name: Chinese Journal of Nuclear Medicine (Zhonghua Heyixue Zazhi); (China); Journal Volume: 9:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CPB; USES; BLOOD SERUM; DIAGNOSIS; EPILEPSY; LABELLED COMPOUNDS; LIVER CIRRHOSIS; LUPUS; RICKETS; TRITIUM; UROGENITAL SYSTEM DISEASES; BACTERIAL DISEASES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; DIGESTIVE SYSTEM DISEASES; DISEASES; HYDROGEN ISOTOPES; IMMUNE SYSTEM DISEASES; INFECTIOUS DISEASES; ISOTOPES; LIGHT NUCLEI; METABOLIC DISEASES; NERVOUS SYSTEM DISEASES; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPES; SKELETAL DISEASES; TUBERCULOSIS; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6038210
Country of Origin:
China
Language:
Chinese
Other Identifying Numbers:
Journal ID: ISSN 0253-9780; CODEN: CITCD
Submitting Site:
INIS
Size:
Pages: 158-160
Announcement Date:
Mar 01, 1991

Journal Article:

Citation Formats

Shouli, Yang. Clinical applications of HPLC-competitive protein binding assay for serum 25-hydroxyvitamin D. China: N. p., 1989. Web.
Shouli, Yang. Clinical applications of HPLC-competitive protein binding assay for serum 25-hydroxyvitamin D. China.
Shouli, Yang. 1989. "Clinical applications of HPLC-competitive protein binding assay for serum 25-hydroxyvitamin D." China.
@misc{etde_6038210,
title = {Clinical applications of HPLC-competitive protein binding assay for serum 25-hydroxyvitamin D}
author = {Shouli, Yang}
abstractNote = {This report describes the clinical applications of HPLC-competitive protein binding assay for serum 25(OH) Vit D in 156 cases. Serum 25(OH) Vit D of normal human was 33.1 +- 14.8 nmol/L (13.2 +- 5.9 ng/ml), while for various diseases are as follows: rickets, 18.0 +- 9.0 nmol/L (7.2 +- 3.6 ng/ml, n = 36, P < 0.005); hypervitaminosis D, 116.8 +- 31.3 nmol/L (46.7 +- 12.3 ng/ml, n = 6, P < 0.001); renal diseases of children, 25.3 +- 7.3 nmol/L (10.1 +- 2.9 ng/ml, n = 9. P > 0.1); pneumonia of children, 33.8 +- 14.8 nmol/L (13.5 +- 5.9 ng/ml, n = 10, P > 0.5); cirrhosis, 13.8 +- 11.3 nmol/L (5.5 +- 4.5 ng/ml, n = 9, P < 0.001); vasculitis, 25.5 +- 15.3 nmol/L (10.2 +- 6.1 ng/ml, n = 5, P > 0.2); administration of anticonvulsant (1 to 15 years), 19.0 +- 6.5 nmol/L (7.6 +- 2.6 ng/ml, n = 19, P < 0.001); administration of glococorticoids (> 6 months), 15.3 +- 5.0 nmol/L (6.1 +- 2.0 ng/ml, n = 6, P < 0.005); hyperthyroidism, 34.0 +- 23.5 nmol/L (13.6 +- 9.4 ng/ml, n = 13, P > 0.5); pregnant women, 39.8 +- 16.5 nmol/L (15.9 +- 6.6 ng/ml, n = 7, P > 0.1). We found it is a useful reference value for most of the above diseased state especially for differentiation between rickets and hypervitaminosis.}
journal = {Chinese Journal of Nuclear Medicine (Zhonghua Heyixue Zazhi); (China)}
volume = {9:3}
journal type = {AC}
place = {China}
year = {1989}
month = {Aug}
}