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Linear transform of the multi-target survival curve

Journal Article:

Abstract

A completely linear transform of the multi-target survival curve is presented. This enables all data, including those on the shoulder region of the curve, to be analysed. The necessity to make a subjective assessment about which data points to exclude for conventional methods of analysis is, therefore, removed. The analysis has also been adapted to include a 'Pike-Alper' method of assessing dose modification factors. For the data cited this predicts compatibility with the hypothesis of a true oxygen 'dose-modification' whereas the conventional Pike-Alper analysis does not.
Authors:
Watson, J V [1] 
  1. Cambridge Univ. (UK). Dept. of Clinical Oncology and Radiotherapeutics
Publication Date:
Jul 01, 1978
Product Type:
Journal Article
Reference Number:
AIX-10-423337; EDB-79-101422
Resource Relation:
Journal Name: Br. J. Radiol.; (United Kingdom); Journal Volume: 51:607
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ANIMAL CELLS; BIOLOGICAL RADIATION EFFECTS; OXYGEN; RADIOSENSITIVITY EFFECTS; SURVIVAL CURVES; COMPUTER CALCULATIONS; ANOXIA; DOSE-RESPONSE RELATIONSHIPS; ERRORS; MATHEMATICAL MODELS; RADIOSENSITIVITY; RESPONSE MODIFYING FACTORS; BIOLOGICAL EFFECTS; CRYOGENIC FLUIDS; ELEMENTS; FLUIDS; NONMETALS; RADIATION EFFECTS; 560121* - Radiation Effects on Cells- External Source- (-1987)
OSTI ID:
6030805
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: BJRAA
Submitting Site:
INIS
Size:
Pages: 534-538
Announcement Date:

Journal Article:

Citation Formats

Watson, J V. Linear transform of the multi-target survival curve. United Kingdom: N. p., 1978. Web.
Watson, J V. Linear transform of the multi-target survival curve. United Kingdom.
Watson, J V. 1978. "Linear transform of the multi-target survival curve." United Kingdom.
@misc{etde_6030805,
title = {Linear transform of the multi-target survival curve}
author = {Watson, J V}
abstractNote = {A completely linear transform of the multi-target survival curve is presented. This enables all data, including those on the shoulder region of the curve, to be analysed. The necessity to make a subjective assessment about which data points to exclude for conventional methods of analysis is, therefore, removed. The analysis has also been adapted to include a 'Pike-Alper' method of assessing dose modification factors. For the data cited this predicts compatibility with the hypothesis of a true oxygen 'dose-modification' whereas the conventional Pike-Alper analysis does not.}
journal = {Br. J. Radiol.; (United Kingdom)}
volume = {51:607}
journal type = {AC}
place = {United Kingdom}
year = {1978}
month = {Jul}
}