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Computed tomography brain changes in Parkinsonian dementia

Abstract

In order to evaluate the relationship between brain atrophy and the motor and cognitive function in Parkinson's disease, we have evaluated CT changes in 132 consecutive patients and compared them to measures of physical and mental decline, using intercorrelations and variance analysis. The result demonstrated age as a most important factor relating to brain atrophy. After correction for this determinant, it became clear that the motor and cognitive parameters were interdependent but they affected similar CT parameters. The effect of motor decline was the stronger of the two and it was the only one which correlated with cortical atrophy. The results support the notion of subcortical changes underlying the dementia of Parkinson's disease.
Publication Date:
Nov 01, 1987
Product Type:
Journal Article
Reference Number:
DEN-87-015931; EDB-88-003327
Resource Relation:
Journal Name: Neuroradiology; (Germany, Federal Republic of); Journal Volume: 29:6
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; ATROPHY; COMPUTERIZED TOMOGRAPHY; DIAGNOSIS; IMAGES; NERVOUS SYSTEM DISEASES; PATIENTS; BODY; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; NERVOUS SYSTEM; ORGANS; PATHOLOGICAL CHANGES; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
6029345
Research Organizations:
Tel Aviv Univ., Israel. Sackler School of Medicine; Tel Aviv Univ., Israel. Dept. of Statistics
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: NRDYA
Submitting Site:
DEN
Size:
Pages: 535-539
Announcement Date:
Dec 01, 1987

Citation Formats

Inzelberg, R, Teeves, T, Reider, I, Gerlenter, I, and Korczyn, A D. Computed tomography brain changes in Parkinsonian dementia. Germany: N. p., 1987. Web.
Inzelberg, R, Teeves, T, Reider, I, Gerlenter, I, & Korczyn, A D. Computed tomography brain changes in Parkinsonian dementia. Germany.
Inzelberg, R, Teeves, T, Reider, I, Gerlenter, I, and Korczyn, A D. 1987. "Computed tomography brain changes in Parkinsonian dementia." Germany.
@misc{etde_6029345,
title = {Computed tomography brain changes in Parkinsonian dementia}
author = {Inzelberg, R, Teeves, T, Reider, I, Gerlenter, I, and Korczyn, A D}
abstractNote = {In order to evaluate the relationship between brain atrophy and the motor and cognitive function in Parkinson's disease, we have evaluated CT changes in 132 consecutive patients and compared them to measures of physical and mental decline, using intercorrelations and variance analysis. The result demonstrated age as a most important factor relating to brain atrophy. After correction for this determinant, it became clear that the motor and cognitive parameters were interdependent but they affected similar CT parameters. The effect of motor decline was the stronger of the two and it was the only one which correlated with cortical atrophy. The results support the notion of subcortical changes underlying the dementia of Parkinson's disease.}
journal = []
volume = {29:6}
journal type = {AC}
place = {Germany}
year = {1987}
month = {Nov}
}