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Effect of protein malnutrition on the metabolism of bone collagen in albino rats

Journal Article:

Abstract

The effect of protein malnutrition on the metabolism of collagen in bone was studied in young female albino rats after a single injection of /sup 3/H-proline. Both specific and total radioactivities of hydroxyproline in the total collagen of the bone were found to decrease in the protein-deficient animals, indicating decreased rate of collagen synthesis. In the urine the amount of hydroxyproline excreted and total radioactivity of /sup 3/H-hydroxyproline were greatly decreased. The results of the present investigation therefore clearly indicate decreased synthesis and catabolism of collagen in bones of protein deficient animals compared to controls.
Authors:
Rao, J S; Rao, V H [1] 
  1. Central Leather Research Inst., Madras (India)
Publication Date:
Jan 01, 1981
Product Type:
Journal Article
Reference Number:
AIX-12-641366; EDB-82-032453
Resource Relation:
Journal Name: Leather Sci. (Madras); (India); Journal Volume: 28:1
Subject:
59 BASIC BIOLOGICAL SCIENCES; COLLAGEN; METABOLISM; BIOSYNTHESIS; LABELLED COMPOUNDS; NUTRITIONAL DEFICIENCY; PROLINE; RATS; SKELETON; TRACER TECHNIQUES; TRITIUM COMPOUNDS; AMINES; AMINO ACIDS; ANIMALS; AZOLES; BODY; CARBOXYLIC ACIDS; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; ISOTOPE APPLICATIONS; MAMMALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PROTEINS; PYRROLES; PYRROLIDINES; RODENTS; SCLEROPROTEINS; SYNTHESIS; VERTEBRATES; 550501* - Metabolism- Tracer Techniques
OSTI ID:
6029166
Country of Origin:
India
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: LESCA
Submitting Site:
INIS
Size:
Pages: 1-4
Announcement Date:
Dec 01, 1981

Journal Article:

Citation Formats

Rao, J S, and Rao, V H. Effect of protein malnutrition on the metabolism of bone collagen in albino rats. India: N. p., 1981. Web.
Rao, J S, & Rao, V H. Effect of protein malnutrition on the metabolism of bone collagen in albino rats. India.
Rao, J S, and Rao, V H. 1981. "Effect of protein malnutrition on the metabolism of bone collagen in albino rats." India.
@misc{etde_6029166,
title = {Effect of protein malnutrition on the metabolism of bone collagen in albino rats}
author = {Rao, J S, and Rao, V H}
abstractNote = {The effect of protein malnutrition on the metabolism of collagen in bone was studied in young female albino rats after a single injection of /sup 3/H-proline. Both specific and total radioactivities of hydroxyproline in the total collagen of the bone were found to decrease in the protein-deficient animals, indicating decreased rate of collagen synthesis. In the urine the amount of hydroxyproline excreted and total radioactivity of /sup 3/H-hydroxyproline were greatly decreased. The results of the present investigation therefore clearly indicate decreased synthesis and catabolism of collagen in bones of protein deficient animals compared to controls.}
journal = {Leather Sci. (Madras); (India)}
volume = {28:1}
journal type = {AC}
place = {India}
year = {1981}
month = {Jan}
}