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Effects of ethylenediaminetetraacetic acid (EDTA)and diethylenetriaminepentaacetic acid (DTPA) derivatives on penetration of ytterbium-169 and cerium-144 into the rat offspring

Journal Article:

Abstract

Penetration of radioactive ytterbum-169 and cerium-144 into fetuses was determined at the end of pregnancy and penetration into the organism of suckling rats was studied during feeding with the milk of exposed mothers when EDTA or DTPA derivatives were being administered. Injection of ytterbum-169 as a complex with EDTA or DTPA or injection of Na/sub 2/Ca EDTA or Na/sub 3/Ca DTPA 1h after administration of cerium-144 to mothers reduced penetration of both radionuclides into offsprings in relation to the animals receiving no complex compounds. It was observed that the action of DTPA was stronger than that of EDTA. Passage of ytterbium with milk and across the placenta was greater than the passage of cerium.
Authors:
Baltrukiewicz, Z; Burakowski, T; Derecki, J [1] 
  1. Wojskowy Inst. Higieny i Epidemiologii, Warsaw (Poland)
Publication Date:
Jan 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-10-445051; EDB-79-120489
Resource Relation:
Journal Name: Acta Physiol. Pol.; (Poland); Journal Volume: 27:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CERIUM 144; RADIONUCLIDE KINETICS; YTTERBIUM 169; DTPA; EDTA; FEEDING; FETUSES; MILK; NEONATES; PLACENTA; PREGNANCY; PROGENY; RATS; AMINO ACIDS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BODY FLUIDS; CARBOXYLIC ACIDS; CERIUM ISOTOPES; CHELATING AGENTS; DAYS LIVING RADIOISOTOPES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-EVEN NUCLEI; EVEN-ODD NUCLEI; FETAL MEMBRANES; FOOD; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MEMBRANES; MINUTES LIVING RADIOISOTOPES; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RARE EARTH ISOTOPES; RARE EARTH NUCLEI; RESPONSE MODIFYING FACTORS; RODENTS; VERTEBRATES; YTTERBIUM ISOTOPES; 560172* - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)
OSTI ID:
5998705
Country of Origin:
Poland
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: APYPA
Submitting Site:
INIS
Size:
Pages: 175-181
Announcement Date:
May 01, 1979

Journal Article:

Citation Formats

Baltrukiewicz, Z, Burakowski, T, and Derecki, J. Effects of ethylenediaminetetraacetic acid (EDTA)and diethylenetriaminepentaacetic acid (DTPA) derivatives on penetration of ytterbium-169 and cerium-144 into the rat offspring. Poland: N. p., 1976. Web.
Baltrukiewicz, Z, Burakowski, T, & Derecki, J. Effects of ethylenediaminetetraacetic acid (EDTA)and diethylenetriaminepentaacetic acid (DTPA) derivatives on penetration of ytterbium-169 and cerium-144 into the rat offspring. Poland.
Baltrukiewicz, Z, Burakowski, T, and Derecki, J. 1976. "Effects of ethylenediaminetetraacetic acid (EDTA)and diethylenetriaminepentaacetic acid (DTPA) derivatives on penetration of ytterbium-169 and cerium-144 into the rat offspring." Poland.
@misc{etde_5998705,
title = {Effects of ethylenediaminetetraacetic acid (EDTA)and diethylenetriaminepentaacetic acid (DTPA) derivatives on penetration of ytterbium-169 and cerium-144 into the rat offspring}
author = {Baltrukiewicz, Z, Burakowski, T, and Derecki, J}
abstractNote = {Penetration of radioactive ytterbum-169 and cerium-144 into fetuses was determined at the end of pregnancy and penetration into the organism of suckling rats was studied during feeding with the milk of exposed mothers when EDTA or DTPA derivatives were being administered. Injection of ytterbum-169 as a complex with EDTA or DTPA or injection of Na/sub 2/Ca EDTA or Na/sub 3/Ca DTPA 1h after administration of cerium-144 to mothers reduced penetration of both radionuclides into offsprings in relation to the animals receiving no complex compounds. It was observed that the action of DTPA was stronger than that of EDTA. Passage of ytterbium with milk and across the placenta was greater than the passage of cerium.}
journal = {Acta Physiol. Pol.; (Poland)}
volume = {27:2}
journal type = {AC}
place = {Poland}
year = {1976}
month = {Jan}
}