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Effect of ionizing radiation on macrophage stimulating property of Vibrio parahaemolyticus lipopolysaccharide

Journal Article:

Abstract

Effect of gamma radiation on the macrophage stimulating ability of Vibrio parahaemolyticus lipopolysaccharide (LPS) was examined. Radiodetoxified LPS (RLPS) when injected (ip) in mice stimulated peritoneal macrophages as was evident from the enhancement of their acid hydrolases and cellular RNA contents. RLPS also stimulated the phagocytic activities of macrophages. The stimulation of macrophages was slightly less as compared to that observed with n ative LPS. Thus, treatment of LPS with 15 kGy dose of gamma radiation results in a slight reduction in its macrophage stimulating ability. (author). 3 tabs., 22 refs.
Publication Date:
Sep 01, 1988
Product Type:
Journal Article
Reference Number:
AIX-20-055926; EDB-89-111147
Resource Relation:
Journal Name: Indian J. Exp. Biol.; (India); Journal Volume: 26:9
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ENDOTOXINS; RADIOLYSIS; LIPOPOLYSACCHARIDES; BACTERIA; CATHEPSIN; DETOXIFICATION; GAMMA RADIATION; GLUCURONIDASE; LYSOZYME; MACROPHAGES; MICE; PHAGOCYTOSIS; ANIMAL CELLS; ANIMALS; ANTIGENS; CARBOHYDRATES; CHEMICAL RADIATION EFFECTS; CHEMICAL REACTIONS; CHEMISTRY; CONNECTIVE TISSUE CELLS; DECOMPOSITION; ELECTROMAGNETIC RADIATION; ENZYMES; GLYCOSYL HYDROLASES; HYDROLASES; IONIZING RADIATIONS; LIPIDS; MAMMALS; MATERIALS; MICROORGANISMS; O-GLYCOSYL HYDROLASES; ORGANIC COMPOUNDS; PHAGOCYTES; POLYSACCHARIDES; RADIATION CHEMISTRY; RADIATION EFFECTS; RADIATIONS; RODENTS; SACCHARIDES; SOMATIC CELLS; TOXIC MATERIALS; TOXINS; VERTEBRATES; 560120* - Radiation Effects on Biochemicals, Cells, & Tissue Culture
OSTI ID:
5996068
Research Organizations:
Bhabha Atomic Research Centre, Bombay (India). Food Technology and Enzyme Engineering Div.
Country of Origin:
India
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: IJEBA
Submitting Site:
INIS
Size:
Pages: 661-664
Announcement Date:

Journal Article:

Citation Formats

Bandekar, J R, Nene, S P, and Nerkar, D P. Effect of ionizing radiation on macrophage stimulating property of Vibrio parahaemolyticus lipopolysaccharide. India: N. p., 1988. Web.
Bandekar, J R, Nene, S P, & Nerkar, D P. Effect of ionizing radiation on macrophage stimulating property of Vibrio parahaemolyticus lipopolysaccharide. India.
Bandekar, J R, Nene, S P, and Nerkar, D P. 1988. "Effect of ionizing radiation on macrophage stimulating property of Vibrio parahaemolyticus lipopolysaccharide." India.
@misc{etde_5996068,
title = {Effect of ionizing radiation on macrophage stimulating property of Vibrio parahaemolyticus lipopolysaccharide}
author = {Bandekar, J R, Nene, S P, and Nerkar, D P}
abstractNote = {Effect of gamma radiation on the macrophage stimulating ability of Vibrio parahaemolyticus lipopolysaccharide (LPS) was examined. Radiodetoxified LPS (RLPS) when injected (ip) in mice stimulated peritoneal macrophages as was evident from the enhancement of their acid hydrolases and cellular RNA contents. RLPS also stimulated the phagocytic activities of macrophages. The stimulation of macrophages was slightly less as compared to that observed with n ative LPS. Thus, treatment of LPS with 15 kGy dose of gamma radiation results in a slight reduction in its macrophage stimulating ability. (author). 3 tabs., 22 refs.}
journal = {Indian J. Exp. Biol.; (India)}
volume = {26:9}
journal type = {AC}
place = {India}
year = {1988}
month = {Sep}
}