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Fundamental evaluation of in vivo labeling of red blood cells with Tc-99m using stannous chloride

Journal Article:

Abstract

Stannous chloride was evaluated as a stannous ion source for the in vivo labeling of red blood cells(RBC) with Tc-99m. In this study, the labeling of RBC with Tc-99m was performed by two successive intravenous administrations of stannous chloride and Tc-99m-pertechnetate, and the optimal dose of stannous chloride and the optimal time interval between the two injections were evaluated. The labeling efficiency for this procedure was also evaluated as a function of time after the pertechnetate injection. The results of our investigation revealed that the maximal in vivo RBC labeling (86%) can be obtained at 15 min after the pertechnetate injection with an i.v. dose of 12.7 ..mu..g/kg of stannous chloride followed 15 min later by an i.v. injection of Tc-99m-pertechnetate. In conclusion, stannous chloride was found to be an excellent stannous ion source for the in vivo labeling of RBC with Tc-99m.
Authors:
Hiraki, T; Katayama, M; Ando, I; Ando, A; [1]  Hisada, K
  1. Kanazawa Univ. (Japan). School of Paramedicine
Publication Date:
Apr 01, 1982
Product Type:
Journal Article
Reference Number:
AIX-14-771805; EDB-83-162492
Resource Relation:
Journal Name: Kaku Igaku; (Japan); Journal Volume: 19:3
Subject:
59 BASIC BIOLOGICAL SCIENCES; ERYTHROCYTES; LABELLING; TECHNETIUM 99; TRACER TECHNIQUES; TIN CHLORIDES; BIOLOGICAL LOCALIZATION; EXCRETION; IN VIVO; INTRAVENOUS INJECTION; RADIONUCLIDE KINETICS; RATS; TIME DEPENDENCE; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CHLORIDES; CHLORINE COMPOUNDS; CLEARANCE; HALIDES; HALOGEN COMPOUNDS; HOURS LIVING RADIOISOTOPES; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPES; RODENTS; TECHNETIUM ISOTOPES; TIN COMPOUNDS; TIN HALIDES; VERTEBRATES; YEARS LIVING RADIOISOTOPES; 550301* - Cytology- Tracer Techniques
OSTI ID:
5981242
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KAIGB
Submitting Site:
HEDB
Size:
Pages: 339-408
Announcement Date:

Journal Article:

Citation Formats

Hiraki, T, Katayama, M, Ando, I, Ando, A, and Hisada, K. Fundamental evaluation of in vivo labeling of red blood cells with Tc-99m using stannous chloride. Japan: N. p., 1982. Web.
Hiraki, T, Katayama, M, Ando, I, Ando, A, & Hisada, K. Fundamental evaluation of in vivo labeling of red blood cells with Tc-99m using stannous chloride. Japan.
Hiraki, T, Katayama, M, Ando, I, Ando, A, and Hisada, K. 1982. "Fundamental evaluation of in vivo labeling of red blood cells with Tc-99m using stannous chloride." Japan.
@misc{etde_5981242,
title = {Fundamental evaluation of in vivo labeling of red blood cells with Tc-99m using stannous chloride}
author = {Hiraki, T, Katayama, M, Ando, I, Ando, A, and Hisada, K}
abstractNote = {Stannous chloride was evaluated as a stannous ion source for the in vivo labeling of red blood cells(RBC) with Tc-99m. In this study, the labeling of RBC with Tc-99m was performed by two successive intravenous administrations of stannous chloride and Tc-99m-pertechnetate, and the optimal dose of stannous chloride and the optimal time interval between the two injections were evaluated. The labeling efficiency for this procedure was also evaluated as a function of time after the pertechnetate injection. The results of our investigation revealed that the maximal in vivo RBC labeling (86%) can be obtained at 15 min after the pertechnetate injection with an i.v. dose of 12.7 ..mu..g/kg of stannous chloride followed 15 min later by an i.v. injection of Tc-99m-pertechnetate. In conclusion, stannous chloride was found to be an excellent stannous ion source for the in vivo labeling of RBC with Tc-99m.}
journal = {Kaku Igaku; (Japan)}
volume = {19:3}
journal type = {AC}
place = {Japan}
year = {1982}
month = {Apr}
}