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Effects of tritiated water on mice liver, in relation to age

Abstract

Tritiated water was administered intraperitoneally at the dose rate of about 20 ..mu..Ci/ml of body water to different six age groups of Swiss albino mice, ranging from 1 to 6 weeks old. They were autopsied at 48 hours post-injection. The liver of 5 weeks old mice is found most vulnerable and that of 4 weeks second but lesser than 5 weeks. Histopathologically, 1, 2, 3 and 6 weeks old mice liver showed lesser degree of damage. The distinct histopathological lesions include oedema, cytoplasmic vacuolation and degranulation, hyperaemia, increase number of Kupffer's cells etc.
Authors:
Bhatia, A L [1] 
  1. Rajasthan Univ., Jaipur (India). Radiation Biology Lab.
Publication Date:
Jun 01, 1978
Product Type:
Journal Article
Reference Number:
AIX-10-445054; EDB-79-120474
Resource Relation:
Journal Name: J. Radiat. Res.; (Japan); Journal Volume: 19:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; LIVER; BIOLOGICAL RADIATION EFFECTS; TRITIUM OXIDES; AGE GROUPS; ANEMIAS; AUTOPSY; CYTOPLASM; EDEMA; HEAVY WATER; INTRAPERITONEAL INJECTION; MICE; MORPHOLOGICAL CHANGES; PHOTOMICROGRAPHY; RETICULOENDOTHELIAL SYSTEM; TIME DEPENDENCE; ANIMALS; BIOLOGICAL EFFECTS; BODY; CELL CONSTITUENTS; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; GLANDS; HEMIC DISEASES; HYDROGEN COMPOUNDS; INJECTION; INTAKE; LABELLED COMPOUNDS; MAMMALS; ORGANS; OXYGEN COMPOUNDS; PATHOLOGICAL CHANGES; PHOTOGRAPHY; RADIATION EFFECTS; RODENTS; SYMPTOMS; TISSUES; TRITIUM COMPOUNDS; VERTEBRATES; WATER; 560171* - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)
OSTI ID:
5973655
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JRARA
Submitting Site:
INIS
Size:
Pages: 153-162
Announcement Date:
May 01, 1979

Citation Formats

Bhatia, A L. Effects of tritiated water on mice liver, in relation to age. Japan: N. p., 1978. Web.
Bhatia, A L. Effects of tritiated water on mice liver, in relation to age. Japan.
Bhatia, A L. 1978. "Effects of tritiated water on mice liver, in relation to age." Japan.
@misc{etde_5973655,
title = {Effects of tritiated water on mice liver, in relation to age}
author = {Bhatia, A L}
abstractNote = {Tritiated water was administered intraperitoneally at the dose rate of about 20 ..mu..Ci/ml of body water to different six age groups of Swiss albino mice, ranging from 1 to 6 weeks old. They were autopsied at 48 hours post-injection. The liver of 5 weeks old mice is found most vulnerable and that of 4 weeks second but lesser than 5 weeks. Histopathologically, 1, 2, 3 and 6 weeks old mice liver showed lesser degree of damage. The distinct histopathological lesions include oedema, cytoplasmic vacuolation and degranulation, hyperaemia, increase number of Kupffer's cells etc.}
journal = []
volume = {19:2}
journal type = {AC}
place = {Japan}
year = {1978}
month = {Jun}
}