Abstract
To examine semiquantitatively regional cerebral blood flow, SPECT with N-isopropyl-p-(I-123)iodoamphetamine (I-123 IMP) was undertaken in 17 patients with Parkinson's disease. Seven patients with Alzheimer's disease and 9 senile control subjects were also imaged for comparison. Both the Parkinson's disease group and the Alzheimer's disease group had a decreased uptake of I-123 IMP in the frontal lobe, in comparison with the control group. A remarkably decreased uptake was seen in the lateral and parietal lobes in the group of Parkinson's disease associated with dementia, as well as in the Alzheimer's disease group. A significantly decreased uptake was observed in the frontal lobe, lateral lobe, thalamus, and basal ganglia in the Parkinson's disease group, irrespective of the presence or absence of dementia. For Parkinson's disease associated with dementia, there was much more significant decrease in I-123 IMP uptake. The pattern of regional cerebral blood flow in the Alzheimer's disease group was analogous to that in the Parkinson's disease group associated with dementia. This supports the hypothesis that Alzheimer's disease may be somewhat involved in the occurrence of dementia for Parkinson's disease. (N.K.).
Citation Formats
Kawabata, Keita, Tachibana, Kyudai, and Sugita, Minoru.
I-123 IMP SPECT in Parkinson's disease; In relation to the presence or absence of dementia.
Japan: N. p.,
1990.
Web.
Kawabata, Keita, Tachibana, Kyudai, & Sugita, Minoru.
I-123 IMP SPECT in Parkinson's disease; In relation to the presence or absence of dementia.
Japan.
Kawabata, Keita, Tachibana, Kyudai, and Sugita, Minoru.
1990.
"I-123 IMP SPECT in Parkinson's disease; In relation to the presence or absence of dementia."
Japan.
@misc{etde_5920688,
title = {I-123 IMP SPECT in Parkinson's disease; In relation to the presence or absence of dementia}
author = {Kawabata, Keita, Tachibana, Kyudai, and Sugita, Minoru}
abstractNote = {To examine semiquantitatively regional cerebral blood flow, SPECT with N-isopropyl-p-(I-123)iodoamphetamine (I-123 IMP) was undertaken in 17 patients with Parkinson's disease. Seven patients with Alzheimer's disease and 9 senile control subjects were also imaged for comparison. Both the Parkinson's disease group and the Alzheimer's disease group had a decreased uptake of I-123 IMP in the frontal lobe, in comparison with the control group. A remarkably decreased uptake was seen in the lateral and parietal lobes in the group of Parkinson's disease associated with dementia, as well as in the Alzheimer's disease group. A significantly decreased uptake was observed in the frontal lobe, lateral lobe, thalamus, and basal ganglia in the Parkinson's disease group, irrespective of the presence or absence of dementia. For Parkinson's disease associated with dementia, there was much more significant decrease in I-123 IMP uptake. The pattern of regional cerebral blood flow in the Alzheimer's disease group was analogous to that in the Parkinson's disease group associated with dementia. This supports the hypothesis that Alzheimer's disease may be somewhat involved in the occurrence of dementia for Parkinson's disease. (N.K.).}
journal = []
volume = {20:6}
journal type = {AC}
place = {Japan}
year = {1990}
month = {Dec}
}
title = {I-123 IMP SPECT in Parkinson's disease; In relation to the presence or absence of dementia}
author = {Kawabata, Keita, Tachibana, Kyudai, and Sugita, Minoru}
abstractNote = {To examine semiquantitatively regional cerebral blood flow, SPECT with N-isopropyl-p-(I-123)iodoamphetamine (I-123 IMP) was undertaken in 17 patients with Parkinson's disease. Seven patients with Alzheimer's disease and 9 senile control subjects were also imaged for comparison. Both the Parkinson's disease group and the Alzheimer's disease group had a decreased uptake of I-123 IMP in the frontal lobe, in comparison with the control group. A remarkably decreased uptake was seen in the lateral and parietal lobes in the group of Parkinson's disease associated with dementia, as well as in the Alzheimer's disease group. A significantly decreased uptake was observed in the frontal lobe, lateral lobe, thalamus, and basal ganglia in the Parkinson's disease group, irrespective of the presence or absence of dementia. For Parkinson's disease associated with dementia, there was much more significant decrease in I-123 IMP uptake. The pattern of regional cerebral blood flow in the Alzheimer's disease group was analogous to that in the Parkinson's disease group associated with dementia. This supports the hypothesis that Alzheimer's disease may be somewhat involved in the occurrence of dementia for Parkinson's disease. (N.K.).}
journal = []
volume = {20:6}
journal type = {AC}
place = {Japan}
year = {1990}
month = {Dec}
}