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Correlation with liver scintigram, reticuloendothelial function test, plasma endotoxin level and liver function tests in chronic liver diseases. Multivariate analysis

Journal Article:

Abstract

Liver scintigrams with Tc-99m phytate were reviewed in a total of 64 consecutive patients, comprising 28 with chronic hepatitis and 36 with liver cirrhosis. Reticuloendothelial (RES) function, plasma endotoxin (Et) levels and findings of general liver function tests were used as reference parameters to determine the diagnostic ability of liver scintigraphy. Multivariate analyses revealed that liver scintigrams had a strong correlation with RES function and Et levels in terms of morphology of the liver and hepatic and bone marrow Tc-99m uptake. General liver function tests revealed gamma globulin to be correlated with hepatic uptake and the degree of splenogemaly on liver scintigrams; and ICG levels at 15 min to be correlated with bone marrow and splenic uptake. Accuracy of liver scintigraphy was 73% for chronic hepatitis, which was inferior to general liver function tests (83%). When both modalities were combined, diangostic accuracy increased to 95%. Liver scintigraphy seems to be useful as a complementary approach. (Namekawa, K).
Publication Date:
Feb 01, 1989
Product Type:
Journal Article
Reference Number:
JPN-89-009503; EDB-89-103276
Resource Relation:
Journal Name: Kan Tan Sui; (Japan); Journal Volume: 18:2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; LIVER; SCINTISCANNING; TECHNETIUM 99; ACCURACY; BIOLOGICAL FUNCTIONS; BONE MARROW; ENDOTOXINS; GLOBULINS-GAMMA; HEPATITIS; LIVER CIRRHOSIS; PATIENTS; RETICULOENDOTHELIAL SYSTEM; SPLEEN; SPLENOMEGALY; STATISTICS; UPTAKE; ANIMAL TISSUES; ANTIGENS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DIGESTIVE SYSTEM DISEASES; DISEASES; FUNCTIONS; GLANDS; GLOBULINS; HEMATOPOIETIC SYSTEM; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATERIALS; MATHEMATICS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; PROTEINS; RADIOISOTOPE SCANNING; RADIOISOTOPES; SYMPTOMS; TECHNETIUM ISOTOPES; TISSUES; TOXIC MATERIALS; TOXINS; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5903970
Research Organizations:
Kawasaki Medical School, Kurashiki, Okayama (Japan)
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KTSUD
Submitting Site:
JPN
Size:
Pages: 351-358
Announcement Date:

Journal Article:

Citation Formats

Ohmoto, Kenji, Yamamoto, Shinichi, and Ideguchi, Seiji and others. Correlation with liver scintigram, reticuloendothelial function test, plasma endotoxin level and liver function tests in chronic liver diseases. Multivariate analysis. Japan: N. p., 1989. Web.
Ohmoto, Kenji, Yamamoto, Shinichi, & Ideguchi, Seiji and others. Correlation with liver scintigram, reticuloendothelial function test, plasma endotoxin level and liver function tests in chronic liver diseases. Multivariate analysis. Japan.
Ohmoto, Kenji, Yamamoto, Shinichi, and Ideguchi, Seiji and others. 1989. "Correlation with liver scintigram, reticuloendothelial function test, plasma endotoxin level and liver function tests in chronic liver diseases. Multivariate analysis." Japan.
@misc{etde_5903970,
title = {Correlation with liver scintigram, reticuloendothelial function test, plasma endotoxin level and liver function tests in chronic liver diseases. Multivariate analysis}
author = {Ohmoto, Kenji, Yamamoto, Shinichi, and Ideguchi, Seiji and others}
abstractNote = {Liver scintigrams with Tc-99m phytate were reviewed in a total of 64 consecutive patients, comprising 28 with chronic hepatitis and 36 with liver cirrhosis. Reticuloendothelial (RES) function, plasma endotoxin (Et) levels and findings of general liver function tests were used as reference parameters to determine the diagnostic ability of liver scintigraphy. Multivariate analyses revealed that liver scintigrams had a strong correlation with RES function and Et levels in terms of morphology of the liver and hepatic and bone marrow Tc-99m uptake. General liver function tests revealed gamma globulin to be correlated with hepatic uptake and the degree of splenogemaly on liver scintigrams; and ICG levels at 15 min to be correlated with bone marrow and splenic uptake. Accuracy of liver scintigraphy was 73% for chronic hepatitis, which was inferior to general liver function tests (83%). When both modalities were combined, diangostic accuracy increased to 95%. Liver scintigraphy seems to be useful as a complementary approach. (Namekawa, K).}
journal = {Kan Tan Sui; (Japan)}
volume = {18:2}
journal type = {AC}
place = {Japan}
year = {1989}
month = {Feb}
}