Abstract
The role of radiotherapy in the treatment of oral Kaposi's sarcoma needs to be defined. Over the past six years, 400 patients with AIDS-related epidemic Kaposi's sarcoma were referred to the oncology department of Henri Mondor Hospital; about 50% had oral Kaposi's lesions. Only 29 of the latter group had received oral cavity irradiation; palliation of pain was the most common indication. The age range was from 26-46 yr with a mean of 36 yr. Twenty-five patients were treated by megavolt age irradiation (4 MV X-rays) 22 of whom received 15 Gy (2 Gy/fraction, 8 Gy/week) and three 30 Gy (15 Gy followed by 3 weeks rest, then a further series of 15 Gy). Five patients were treated by orthovoltage irradiation (45 kV) and received 10-20 Gy (one patient received the two methods of irradiation). Treatment was generally successful in achieving palliation: of the 22 patients who received 15 Gy, 13.6% achieved complete remission and 86.4% partial remission with disappearance of pain; however, toxicity related to severe mucositis, even at relatively low doses and in spite of anti-mycotic treatment, is an argument for restrictive use of this modality.
Frikha, H;
Le Bourgeois, J P;
Haddad, E;
Piedbois, P;
Le Pechoux, C;
Ghilezan, M;
Mazeron, J J
[1]
- Hopital Henri-Mondor, 94 - Creteil (France)
Citation Formats
Frikha, H, Le Bourgeois, J P, Haddad, E, Piedbois, P, Le Pechoux, C, Ghilezan, M, and Mazeron, J J.
The role of radiotherapy in the treatment of oral Kaposi's sarcoma. Place de la radiotherapie dans le traitement des sarcomes de Kaposi de la cavite buccale.
France: N. p.,
1993.
Web.
Frikha, H, Le Bourgeois, J P, Haddad, E, Piedbois, P, Le Pechoux, C, Ghilezan, M, & Mazeron, J J.
The role of radiotherapy in the treatment of oral Kaposi's sarcoma. Place de la radiotherapie dans le traitement des sarcomes de Kaposi de la cavite buccale.
France.
Frikha, H, Le Bourgeois, J P, Haddad, E, Piedbois, P, Le Pechoux, C, Ghilezan, M, and Mazeron, J J.
1993.
"The role of radiotherapy in the treatment of oral Kaposi's sarcoma. Place de la radiotherapie dans le traitement des sarcomes de Kaposi de la cavite buccale."
France.
@misc{etde_5893615,
title = {The role of radiotherapy in the treatment of oral Kaposi's sarcoma. Place de la radiotherapie dans le traitement des sarcomes de Kaposi de la cavite buccale}
author = {Frikha, H, Le Bourgeois, J P, Haddad, E, Piedbois, P, Le Pechoux, C, Ghilezan, M, and Mazeron, J J}
abstractNote = {The role of radiotherapy in the treatment of oral Kaposi's sarcoma needs to be defined. Over the past six years, 400 patients with AIDS-related epidemic Kaposi's sarcoma were referred to the oncology department of Henri Mondor Hospital; about 50% had oral Kaposi's lesions. Only 29 of the latter group had received oral cavity irradiation; palliation of pain was the most common indication. The age range was from 26-46 yr with a mean of 36 yr. Twenty-five patients were treated by megavolt age irradiation (4 MV X-rays) 22 of whom received 15 Gy (2 Gy/fraction, 8 Gy/week) and three 30 Gy (15 Gy followed by 3 weeks rest, then a further series of 15 Gy). Five patients were treated by orthovoltage irradiation (45 kV) and received 10-20 Gy (one patient received the two methods of irradiation). Treatment was generally successful in achieving palliation: of the 22 patients who received 15 Gy, 13.6% achieved complete remission and 86.4% partial remission with disappearance of pain; however, toxicity related to severe mucositis, even at relatively low doses and in spite of anti-mycotic treatment, is an argument for restrictive use of this modality.}
journal = []
volume = {80:2}
journal type = {AC}
place = {France}
year = {1993}
month = {Jan}
}
title = {The role of radiotherapy in the treatment of oral Kaposi's sarcoma. Place de la radiotherapie dans le traitement des sarcomes de Kaposi de la cavite buccale}
author = {Frikha, H, Le Bourgeois, J P, Haddad, E, Piedbois, P, Le Pechoux, C, Ghilezan, M, and Mazeron, J J}
abstractNote = {The role of radiotherapy in the treatment of oral Kaposi's sarcoma needs to be defined. Over the past six years, 400 patients with AIDS-related epidemic Kaposi's sarcoma were referred to the oncology department of Henri Mondor Hospital; about 50% had oral Kaposi's lesions. Only 29 of the latter group had received oral cavity irradiation; palliation of pain was the most common indication. The age range was from 26-46 yr with a mean of 36 yr. Twenty-five patients were treated by megavolt age irradiation (4 MV X-rays) 22 of whom received 15 Gy (2 Gy/fraction, 8 Gy/week) and three 30 Gy (15 Gy followed by 3 weeks rest, then a further series of 15 Gy). Five patients were treated by orthovoltage irradiation (45 kV) and received 10-20 Gy (one patient received the two methods of irradiation). Treatment was generally successful in achieving palliation: of the 22 patients who received 15 Gy, 13.6% achieved complete remission and 86.4% partial remission with disappearance of pain; however, toxicity related to severe mucositis, even at relatively low doses and in spite of anti-mycotic treatment, is an argument for restrictive use of this modality.}
journal = []
volume = {80:2}
journal type = {AC}
place = {France}
year = {1993}
month = {Jan}
}