Abstract
To know changes in immunological competence of T-cells induced by radiotherapy, T-cells in peripheral blood of patients who underwent radiotherapy were observed before, during, and 6 months after the irradiation. The subjects were 69 patients having malignant tumors including 20 with gastric cancer, 15 with breast cancer, and 9 with colon cancer. 200 rad of an exposure dose was irradiated for successive 5 to 6 days. A total of exposure doses ranged from 2,000 to 10,000 rad. T-cell count decreased markedly until exposure doses reached 3,000 rad, but its decrease was mild after exposure doses were over 3,000 rad. T-cell count decreased slightly in patients whose head and neck were irradiated, but it decreased markedly in patients whose thorax and abdomen were irradiated. Therefore, it was thought that there was a relationship between exposed sites and the decrease in T-cell count. T-cell count decreased markedly when irradiation field was wide. The smaller exposure doses were, the earlier the recovery of T-cell were. T-cells irradiated with over 7,000 rad did not recover within 6 months after the irradiation. The recovery of T-cells in patients with gastric cancer who did not undergo gastrectomy was markedly worse than that in patients who had
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Citation Formats
Makino, K, and Sato, S.
Changes in T-cell count in patients undergoing radiotherapy. With particular reference to preoperative irradiation for gastric carcinoma.
Japan: N. p.,
1980.
Web.
Makino, K, & Sato, S.
Changes in T-cell count in patients undergoing radiotherapy. With particular reference to preoperative irradiation for gastric carcinoma.
Japan.
Makino, K, and Sato, S.
1980.
"Changes in T-cell count in patients undergoing radiotherapy. With particular reference to preoperative irradiation for gastric carcinoma."
Japan.
@misc{etde_5888166,
title = {Changes in T-cell count in patients undergoing radiotherapy. With particular reference to preoperative irradiation for gastric carcinoma}
author = {Makino, K, and Sato, S}
abstractNote = {To know changes in immunological competence of T-cells induced by radiotherapy, T-cells in peripheral blood of patients who underwent radiotherapy were observed before, during, and 6 months after the irradiation. The subjects were 69 patients having malignant tumors including 20 with gastric cancer, 15 with breast cancer, and 9 with colon cancer. 200 rad of an exposure dose was irradiated for successive 5 to 6 days. A total of exposure doses ranged from 2,000 to 10,000 rad. T-cell count decreased markedly until exposure doses reached 3,000 rad, but its decrease was mild after exposure doses were over 3,000 rad. T-cell count decreased slightly in patients whose head and neck were irradiated, but it decreased markedly in patients whose thorax and abdomen were irradiated. Therefore, it was thought that there was a relationship between exposed sites and the decrease in T-cell count. T-cell count decreased markedly when irradiation field was wide. The smaller exposure doses were, the earlier the recovery of T-cell were. T-cells irradiated with over 7,000 rad did not recover within 6 months after the irradiation. The recovery of T-cells in patients with gastric cancer who did not undergo gastrectomy was markedly worse than that in patients who had gastrectomy. Patterns of changes in T-cell count were divided into 4 (ascending curve, U-type curve, flat curve, and descending curve), and prognosis of patients were discussed. There was a clear difference in prognosis of patients among four patterns.}
journal = []
volume = {41:1}
journal type = {AC}
place = {Japan}
year = {1980}
month = {Jan}
}
title = {Changes in T-cell count in patients undergoing radiotherapy. With particular reference to preoperative irradiation for gastric carcinoma}
author = {Makino, K, and Sato, S}
abstractNote = {To know changes in immunological competence of T-cells induced by radiotherapy, T-cells in peripheral blood of patients who underwent radiotherapy were observed before, during, and 6 months after the irradiation. The subjects were 69 patients having malignant tumors including 20 with gastric cancer, 15 with breast cancer, and 9 with colon cancer. 200 rad of an exposure dose was irradiated for successive 5 to 6 days. A total of exposure doses ranged from 2,000 to 10,000 rad. T-cell count decreased markedly until exposure doses reached 3,000 rad, but its decrease was mild after exposure doses were over 3,000 rad. T-cell count decreased slightly in patients whose head and neck were irradiated, but it decreased markedly in patients whose thorax and abdomen were irradiated. Therefore, it was thought that there was a relationship between exposed sites and the decrease in T-cell count. T-cell count decreased markedly when irradiation field was wide. The smaller exposure doses were, the earlier the recovery of T-cell were. T-cells irradiated with over 7,000 rad did not recover within 6 months after the irradiation. The recovery of T-cells in patients with gastric cancer who did not undergo gastrectomy was markedly worse than that in patients who had gastrectomy. Patterns of changes in T-cell count were divided into 4 (ascending curve, U-type curve, flat curve, and descending curve), and prognosis of patients were discussed. There was a clear difference in prognosis of patients among four patterns.}
journal = []
volume = {41:1}
journal type = {AC}
place = {Japan}
year = {1980}
month = {Jan}
}