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Measurement of serum FT/sub 4/ in pregnancy and binding protein abnormalities by different methods

Conference:

Abstract

In serum of pregnant women in the 3rd trimester, the majority of FT/sub 4/ methods compared in the present study yielded FT/sub 4/ concentrations in the lower parts of normal ranges or beyond the lower normal border lines. In TBG deficiency, serum FT/sub 4/ as measured by six FT/sub 4/ kits was found to be in the manufacturer-specified normal ranges and did not show clearly recognizable systematic differences between single kits or kit groups with different methodological principles. considerable kit-dependent differences of measured FT/sub 4/ were found in euthyroid patients with TBG excess; all values were, however, in the respective normal ranges. In dysalbuminemic hyperthyroxinemia, labelled analogue kits yielded falsely elevated FT/sub 4/ concentrations, while FT/sub 4/ measured by non-analogue methods was normal in agreement with the euthyroid status of the patient.
Publication Date:
Nov 01, 1985
Product Type:
Conference
Report Number:
CONF-8505276-
Reference Number:
DEN-86-004564; EDB-86-104415
Resource Relation:
Journal Name: Nuc Compact, Compact News Nucl. Med.; (Germany, Federal Republic of); Journal Volume: 16:6; Conference: International symposium on clinical significance and reliability of free thyroid hormone estimation, Berlin, F.R. Germany, 15 May 1985
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; PREGNANCY; BLOOD CHEMISTRY; THYROXINE; RADIOIMMUNOASSAY; ACCURACY; BLOOD SERUM; COMPARATIVE EVALUATIONS; ERRORS; PATIENTS; PROTEINS; QUANTITY RATIO; WOMEN; AMINO ACIDS; ANIMALS; CARBOXYLIC ACIDS; FEMALES; HORMONES; IMMUNOASSAY; IMMUNOLOGY; ISOTOPE APPLICATIONS; MAMMALS; MAN; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; PEPTIDE HORMONES; PRIMATES; RADIOASSAY; RADIOIMMUNOLOGY; THYROID HORMONES; TRACER TECHNIQUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5882649
Research Organizations:
Freie Univ. Berlin, Germany, F.R. Abt. fuer Nuklearmedizin
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: CNNMA
Submitting Site:
DEN
Size:
Pages: 365-366
Announcement Date:

Conference:

Citation Formats

Meinhold, H, and Wenzel, K W. Measurement of serum FT/sub 4/ in pregnancy and binding protein abnormalities by different methods. Germany: N. p., 1985. Web.
Meinhold, H, & Wenzel, K W. Measurement of serum FT/sub 4/ in pregnancy and binding protein abnormalities by different methods. Germany.
Meinhold, H, and Wenzel, K W. 1985. "Measurement of serum FT/sub 4/ in pregnancy and binding protein abnormalities by different methods." Germany.
@misc{etde_5882649,
title = {Measurement of serum FT/sub 4/ in pregnancy and binding protein abnormalities by different methods}
author = {Meinhold, H, and Wenzel, K W}
abstractNote = {In serum of pregnant women in the 3rd trimester, the majority of FT/sub 4/ methods compared in the present study yielded FT/sub 4/ concentrations in the lower parts of normal ranges or beyond the lower normal border lines. In TBG deficiency, serum FT/sub 4/ as measured by six FT/sub 4/ kits was found to be in the manufacturer-specified normal ranges and did not show clearly recognizable systematic differences between single kits or kit groups with different methodological principles. considerable kit-dependent differences of measured FT/sub 4/ were found in euthyroid patients with TBG excess; all values were, however, in the respective normal ranges. In dysalbuminemic hyperthyroxinemia, labelled analogue kits yielded falsely elevated FT/sub 4/ concentrations, while FT/sub 4/ measured by non-analogue methods was normal in agreement with the euthyroid status of the patient.}
journal = {Nuc Compact, Compact News Nucl. Med.; (Germany, Federal Republic of)}
volume = {16:6}
place = {Germany}
year = {1985}
month = {Nov}
}