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Aging in Hiroshima and Nagasaki atomic bomb survivors: soluble--insoluble collagen ratio

Technical Report:

Abstract

The soluble--insoluble collagen ratio was determined in aortas removed at autopsy during the period 1966--70 (21--25 years post-exposure); 261 specimens were examined from persons of both sexes, age 30--89 years at death. A portion of the test samples were from persons located less than 1500 m from the hypocenter at the time of the bomb. The ratio in this group was not significantly different from persons who were not in Hiroshima and Nagasaki at the time of the explosions. However, a possible discrepancy was noted between the two exposure groups involving both males and females who were less than 60 years of age at the time of death with lower average values among the exposed groups. This observation is interpreted and related to the pronounced life-shortening effect of radiation when animals are exposed at a young age. (DLC)
Publication Date:
Jan 01, 1973
Product Type:
Technical Report
Report Number:
ABCC-TR-11-72
Reference Number:
EDB-80-006922
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; LIFE CYCLE; DELAYED RADIATION EFFECTS; AORTA; COLLAGEN; HIROSHIMA; LIFE SPAN; NAGASAKI; SEX; SOLUBILITY; ARTERIES; ASIA; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; JAPAN; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIATION EFFECTS; SCLEROPROTEINS; 560151* - Radiation Effects on Animals- Man
OSTI ID:
5867926
Research Organizations:
Atomic Bomb Casualty Commission, Hiroshima (Japan); Atomic Bomb Casualty Commission, Nagasaki (Japan)
Country of Origin:
Japan
Language:
English and Japanese
Contract Number:
EX-76-C-28-3161
Availability:
Dep. NTIS, PC A02/MF A01.
Submitting Site:
TIC
Size:
Pages: 7
Announcement Date:

Technical Report:

Citation Formats

Anderson, R E, Yamamoto, T, and Thorslund, T W. Aging in Hiroshima and Nagasaki atomic bomb survivors: soluble--insoluble collagen ratio. Japan: N. p., 1973. Web.
Anderson, R E, Yamamoto, T, & Thorslund, T W. Aging in Hiroshima and Nagasaki atomic bomb survivors: soluble--insoluble collagen ratio. Japan.
Anderson, R E, Yamamoto, T, and Thorslund, T W. 1973. "Aging in Hiroshima and Nagasaki atomic bomb survivors: soluble--insoluble collagen ratio." Japan.
@misc{etde_5867926,
title = {Aging in Hiroshima and Nagasaki atomic bomb survivors: soluble--insoluble collagen ratio}
author = {Anderson, R E, Yamamoto, T, and Thorslund, T W}
abstractNote = {The soluble--insoluble collagen ratio was determined in aortas removed at autopsy during the period 1966--70 (21--25 years post-exposure); 261 specimens were examined from persons of both sexes, age 30--89 years at death. A portion of the test samples were from persons located less than 1500 m from the hypocenter at the time of the bomb. The ratio in this group was not significantly different from persons who were not in Hiroshima and Nagasaki at the time of the explosions. However, a possible discrepancy was noted between the two exposure groups involving both males and females who were less than 60 years of age at the time of death with lower average values among the exposed groups. This observation is interpreted and related to the pronounced life-shortening effect of radiation when animals are exposed at a young age. (DLC)}
place = {Japan}
year = {1973}
month = {Jan}
}