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Serum immunoglobulin levels in atomic bomb survivors, Hiroshima

Abstract

Serum immunoglobulins (SI) were determined in 803 survivors and matched controls. Each subject's age, sex, health, exposure, and medical record were evaluated with respect to serum IgG, IgA, IgM levels. The IgG and IgA levels tended to be higher for this Hiroshima population than for Americans. Past exposure to ionizing radiation showed no significant correlation to SI levels. However, age and sex did influence the SI. IgM was significantly higher in females. With advancing age IgG and IgA increased in males, and IgM decreased in females. Elevated sedimentation rate and increased lymphocytes were accompanied by increased SI levels. Radiographic TB was detected in 45% of the population; IgG and IgA levels were somewhat elevated in these individuals. (DLC)
Publication Date:
Jan 01, 1972
Product Type:
Technical Report
Report Number:
ABCC-TR-25-72
Reference Number:
EDB-80-006940
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; IMMUNOGLOBULINS; BLOOD SERUM; AGE DEPENDENCE; BIOLOGICAL RADIATION EFFECTS; HIROSHIMA; HUMAN POPULATIONS; SEX; TUBERCULOSIS; ASIA; BIOLOGICAL EFFECTS; DISEASES; GLOBULINS; INFECTIOUS DISEASES; JAPAN; ORGANIC COMPOUNDS; POPULATIONS; PROTEINS; RADIATION EFFECTS; 560151* - Radiation Effects on Animals- Man
OSTI ID:
5867897
Research Organizations:
Atomic Bomb Casualty Commission, Hiroshima (Japan)
Country of Origin:
Japan
Language:
English and Japanese
Contract Number:
EX-76-C-28-3161
Availability:
Dep. NTIS, PC A02/MF A01.
Submitting Site:
TIC
Size:
Pages: 19
Announcement Date:
May 13, 2001

Citation Formats

Hall, C B, Hall, W J, Ashley, F W, and Hamilton, H B. Serum immunoglobulin levels in atomic bomb survivors, Hiroshima. Japan: N. p., 1972. Web.
Hall, C B, Hall, W J, Ashley, F W, & Hamilton, H B. Serum immunoglobulin levels in atomic bomb survivors, Hiroshima. Japan.
Hall, C B, Hall, W J, Ashley, F W, and Hamilton, H B. 1972. "Serum immunoglobulin levels in atomic bomb survivors, Hiroshima." Japan.
@misc{etde_5867897,
title = {Serum immunoglobulin levels in atomic bomb survivors, Hiroshima}
author = {Hall, C B, Hall, W J, Ashley, F W, and Hamilton, H B}
abstractNote = {Serum immunoglobulins (SI) were determined in 803 survivors and matched controls. Each subject's age, sex, health, exposure, and medical record were evaluated with respect to serum IgG, IgA, IgM levels. The IgG and IgA levels tended to be higher for this Hiroshima population than for Americans. Past exposure to ionizing radiation showed no significant correlation to SI levels. However, age and sex did influence the SI. IgM was significantly higher in females. With advancing age IgG and IgA increased in males, and IgM decreased in females. Elevated sedimentation rate and increased lymphocytes were accompanied by increased SI levels. Radiographic TB was detected in 45% of the population; IgG and IgA levels were somewhat elevated in these individuals. (DLC)}
place = {Japan}
year = {1972}
month = {Jan}
}