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Method for monitoring the course of oxidation of iodide ion during radioactive iodination operation

Abstract

A micro-iodine ion selective electrode is developed to follow and monitor the course of oxidation of iodide ion during radioactive iodination operation. The experimental results indicate that this method can quickly respond to the course of oxidation if the reacting liquid is greater than 30 micro liter in volume. Therefore it can be used for accurate controlling the amount of oxidzing reagent used for the reaction, for example, the amount of chloroamine T can be reduced to 1/40 of the amount ordinarily used for the preparation of angiotonin II and insulin. The effect of pH and concentration of phosphate of the reacting liquid to the oxidation reaction of I with chloroamine T is also studied.
Authors:
Publication Date:
May 01, 1986
Product Type:
Journal Article
Reference Number:
AIX-18-097808; EDB-88-018530
Resource Relation:
Journal Name: At. Energy Sci. Technol. (Engl. Transl.); (China); Journal Volume: 20:3
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; IODIDES; ION SELECTIVE ELECTRODE ANALYSIS; OXIDATION; ANGIOTENSIN; CHLORAMINES; INSULIN; IODINATION; IODINE 125; PH VALUE; PHOSPHATES; QUANTITY RATIO; AMINES; BETA DECAY RADIOISOTOPES; CARDIOVASCULAR AGENTS; CHEMICAL ANALYSIS; CHEMICAL REACTIONS; DAYS LIVING RADIOISOTOPES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; GLOBULINS; HALIDES; HALOGEN COMPOUNDS; HALOGENATION; HORMONES; INTERMEDIATE MASS NUCLEI; IODINE COMPOUNDS; IODINE ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC CHLORINE COMPOUNDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; OXYGEN COMPOUNDS; PEPTIDE HORMONES; PHOSPHORUS COMPOUNDS; PROTEINS; RADIOISOTOPES; VASOCONSTRICTORS; 400102* - Chemical & Spectral Procedures
OSTI ID:
5846751
Research Organizations:
Academia Sinica, Beijing, China. Inst. of Atomic Energy
Country of Origin:
China
Language:
Chinese
Other Identifying Numbers:
Journal ID: CODEN: YKJIE
Submitting Site:
INIS
Size:
Pages: 320-324
Announcement Date:
Dec 01, 1987

Citation Formats

Xuezhong, Luo. Method for monitoring the course of oxidation of iodide ion during radioactive iodination operation. China: N. p., 1986. Web.
Xuezhong, Luo. Method for monitoring the course of oxidation of iodide ion during radioactive iodination operation. China.
Xuezhong, Luo. 1986. "Method for monitoring the course of oxidation of iodide ion during radioactive iodination operation." China.
@misc{etde_5846751,
title = {Method for monitoring the course of oxidation of iodide ion during radioactive iodination operation}
author = {Xuezhong, Luo}
abstractNote = {A micro-iodine ion selective electrode is developed to follow and monitor the course of oxidation of iodide ion during radioactive iodination operation. The experimental results indicate that this method can quickly respond to the course of oxidation if the reacting liquid is greater than 30 micro liter in volume. Therefore it can be used for accurate controlling the amount of oxidzing reagent used for the reaction, for example, the amount of chloroamine T can be reduced to 1/40 of the amount ordinarily used for the preparation of angiotonin II and insulin. The effect of pH and concentration of phosphate of the reacting liquid to the oxidation reaction of I with chloroamine T is also studied.}
journal = []
volume = {20:3}
journal type = {AC}
place = {China}
year = {1986}
month = {May}
}