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Protective effect of intermittent fasting on the mortality of gamma-irradiated mice

Journal Article:

Abstract

The effect of 1 to 6 weeks' adaptation to intermittent fasting (alternating periods of 24 h fasting and subsequent 24 h feeding) on the manifestations of radioresistance of mice subjected to whole-body gamma-irradiation was studied. A favourable effect of this feeding regimen on the survival of irradiated animals was observed. The optimal redioprotective effect was achieved in mice adapted to intermittent fasting for 2 to 3 weeks and irradiated after 24 h of food intake. Furthermore, it was shown that the radioresistance of the adapted organism depends on the momentary state of food intake. After renewal of the normal ad libitum feeding the adaptively induced radioresistance decreases.
Publication Date:
Dec 01, 1982
Product Type:
Journal Article
Reference Number:
EDB-83-152727
Resource Relation:
Journal Name: Strahlentherapie; (Germany, Federal Republic of); Journal Volume: 158:12
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; FASTING; RADIATION PROTECTION; RADIATION INJURIES; RESPONSE MODIFYING FACTORS; DIET; GAMMA RADIATION; LETHAL RADIATION DOSE; MICE; MORTALITY; NUTRITIONAL DEFICIENCY; SURVIVAL CURVES; WHOLE-BODY IRRADIATION; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; DOSES; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; INJURIES; IONIZING RADIATIONS; IRRADIATION; LETHAL DOSES; MAMMALS; RADIATION DOSES; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
5835950
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: STRAA
Submitting Site:
HEDB
Size:
Pages: 734-738
Announcement Date:
Apr 01, 1983

Journal Article:

Citation Formats

Kozubik, A, and Pospisil, M. Protective effect of intermittent fasting on the mortality of gamma-irradiated mice. Germany: N. p., 1982. Web.
Kozubik, A, & Pospisil, M. Protective effect of intermittent fasting on the mortality of gamma-irradiated mice. Germany.
Kozubik, A, and Pospisil, M. 1982. "Protective effect of intermittent fasting on the mortality of gamma-irradiated mice." Germany.
@misc{etde_5835950,
title = {Protective effect of intermittent fasting on the mortality of gamma-irradiated mice}
author = {Kozubik, A, and Pospisil, M}
abstractNote = {The effect of 1 to 6 weeks' adaptation to intermittent fasting (alternating periods of 24 h fasting and subsequent 24 h feeding) on the manifestations of radioresistance of mice subjected to whole-body gamma-irradiation was studied. A favourable effect of this feeding regimen on the survival of irradiated animals was observed. The optimal redioprotective effect was achieved in mice adapted to intermittent fasting for 2 to 3 weeks and irradiated after 24 h of food intake. Furthermore, it was shown that the radioresistance of the adapted organism depends on the momentary state of food intake. After renewal of the normal ad libitum feeding the adaptively induced radioresistance decreases.}
journal = {Strahlentherapie; (Germany, Federal Republic of)}
volume = {158:12}
journal type = {AC}
place = {Germany}
year = {1982}
month = {Dec}
}