Abstract
Blood from a splenectomized calf infected with Babesia major was divided into 20 ml aliquots which were ..gamma..-irradiated at doses of 0, 23.3, 27.3, 31.4, 35.4 and 39.5 krad and then inoculated into groups of three intact calves. Animals receiving non-irradiated blood had typical mild B. major reactions, but those receiving blood irradiated at 23.3, 27.3 and 31.4 krad and 2 of 3 receiving blood irradiated at 35.4 krad had minimal reactions. The remaining 4 animals had no detectable parasitaemic reactions. When the calves were challenged with a similar number (6.0 x 10/sup 9/) of homologous parasites, they were all immune with the exception of the 4 animals which had not reacted initially. The immune status of individual cattle was reflected accurately in the results of the micro-ELISA test, which detected a significant rise in serum antibody titre of the 4 susceptible animals 7 days after challenge.
Purnell, R E;
Lewis, D;
Brocklesby, D W
[1]
- Agricultural Research Council, Compton (UK). Inst. for Research on Animal Diseases
Citation Formats
Purnell, R E, Lewis, D, and Brocklesby, D W.
Babesia major: protection of intact calves against homologous challenge by the injection of irradiated piroplasms.
United Kingdom: N. p.,
1979.
Web.
doi:10.1016/0020-7519(79)90069-9.
Purnell, R E, Lewis, D, & Brocklesby, D W.
Babesia major: protection of intact calves against homologous challenge by the injection of irradiated piroplasms.
United Kingdom.
https://doi.org/10.1016/0020-7519(79)90069-9
Purnell, R E, Lewis, D, and Brocklesby, D W.
1979.
"Babesia major: protection of intact calves against homologous challenge by the injection of irradiated piroplasms."
United Kingdom.
https://doi.org/10.1016/0020-7519(79)90069-9.
@misc{etde_5830134,
title = {Babesia major: protection of intact calves against homologous challenge by the injection of irradiated piroplasms}
author = {Purnell, R E, Lewis, D, and Brocklesby, D W}
abstractNote = {Blood from a splenectomized calf infected with Babesia major was divided into 20 ml aliquots which were ..gamma..-irradiated at doses of 0, 23.3, 27.3, 31.4, 35.4 and 39.5 krad and then inoculated into groups of three intact calves. Animals receiving non-irradiated blood had typical mild B. major reactions, but those receiving blood irradiated at 23.3, 27.3 and 31.4 krad and 2 of 3 receiving blood irradiated at 35.4 krad had minimal reactions. The remaining 4 animals had no detectable parasitaemic reactions. When the calves were challenged with a similar number (6.0 x 10/sup 9/) of homologous parasites, they were all immune with the exception of the 4 animals which had not reacted initially. The immune status of individual cattle was reflected accurately in the results of the micro-ELISA test, which detected a significant rise in serum antibody titre of the 4 susceptible animals 7 days after challenge.}
doi = {10.1016/0020-7519(79)90069-9}
journal = []
volume = {9:1}
journal type = {AC}
place = {United Kingdom}
year = {1979}
month = {Feb}
}
title = {Babesia major: protection of intact calves against homologous challenge by the injection of irradiated piroplasms}
author = {Purnell, R E, Lewis, D, and Brocklesby, D W}
abstractNote = {Blood from a splenectomized calf infected with Babesia major was divided into 20 ml aliquots which were ..gamma..-irradiated at doses of 0, 23.3, 27.3, 31.4, 35.4 and 39.5 krad and then inoculated into groups of three intact calves. Animals receiving non-irradiated blood had typical mild B. major reactions, but those receiving blood irradiated at 23.3, 27.3 and 31.4 krad and 2 of 3 receiving blood irradiated at 35.4 krad had minimal reactions. The remaining 4 animals had no detectable parasitaemic reactions. When the calves were challenged with a similar number (6.0 x 10/sup 9/) of homologous parasites, they were all immune with the exception of the 4 animals which had not reacted initially. The immune status of individual cattle was reflected accurately in the results of the micro-ELISA test, which detected a significant rise in serum antibody titre of the 4 susceptible animals 7 days after challenge.}
doi = {10.1016/0020-7519(79)90069-9}
journal = []
volume = {9:1}
journal type = {AC}
place = {United Kingdom}
year = {1979}
month = {Feb}
}