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Diagnostic value of C-peptide determination. [Radioimmunoassay]

Abstract

C-peptide and insulin serum determinations were performed in 94 glucagon-stimulated diabetics and in 15 healthy persons. A minimal increase of 1.5 ng C-peptide/ml serum after glucagon injection (1 mg i.v.) was found to be a useful parameter for the differentiation of insulin dependent and non-insulin dependent diabetics. The maximal response to glucagon occurred during the first 10-minutes after the injection (blood was drawn at 2-minutes intervals). Serum insulin levels and basal C-peptide concentrations were of no value in predicting insulin-dependency. Basal C-peptide levels were significantly different from control in juvenile insulin dependent diabetics (decrease) only.
Authors:
Kober, G; Rainer, O H [1] 
  1. Landeskrankenhaus Klagenfurt (Austria). Nuklearmedizinische Abt.
Publication Date:
Jan 01, 1983
Product Type:
Journal Article
Reference Number:
AIX-14-779188; EDB-83-179584
Resource Relation:
Journal Name: Acta Med. Austriaca; (Austria); Journal Volume: 10:2-3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DIABETES MELLITUS; DIAGNOSIS; INSULIN; RADIOIMMUNOASSAY; BLOOD SERUM; GLUCAGON; PATIENTS; PEPTIDES; QUANTITY RATIO; DISEASES; ENDOCRINE DISEASES; HORMONES; ISOTOPE APPLICATIONS; METABOLIC DISEASES; ORGANIC COMPOUNDS; PEPTIDE HORMONES; POLYPEPTIDES; PROTEINS; RADIOASSAY; TRACER TECHNIQUES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5821043
Country of Origin:
Austria
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: AMAUB
Submitting Site:
HEDB
Size:
Pages: 67-70
Announcement Date:
Aug 01, 1983

Citation Formats

Kober, G, and Rainer, O H. Diagnostic value of C-peptide determination. [Radioimmunoassay]. Austria: N. p., 1983. Web.
Kober, G, & Rainer, O H. Diagnostic value of C-peptide determination. [Radioimmunoassay]. Austria.
Kober, G, and Rainer, O H. 1983. "Diagnostic value of C-peptide determination. [Radioimmunoassay]." Austria.
@misc{etde_5821043,
title = {Diagnostic value of C-peptide determination. [Radioimmunoassay]}
author = {Kober, G, and Rainer, O H}
abstractNote = {C-peptide and insulin serum determinations were performed in 94 glucagon-stimulated diabetics and in 15 healthy persons. A minimal increase of 1.5 ng C-peptide/ml serum after glucagon injection (1 mg i.v.) was found to be a useful parameter for the differentiation of insulin dependent and non-insulin dependent diabetics. The maximal response to glucagon occurred during the first 10-minutes after the injection (blood was drawn at 2-minutes intervals). Serum insulin levels and basal C-peptide concentrations were of no value in predicting insulin-dependency. Basal C-peptide levels were significantly different from control in juvenile insulin dependent diabetics (decrease) only.}
journal = []
volume = {10:2-3}
journal type = {AC}
place = {Austria}
year = {1983}
month = {Jan}
}