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Small cardiac lesions: fibrosis of papillary muscles and focal cardiac myocytolysis

Journal Article:

Abstract

Three types of small cardiac lesions were described and illustrated: (1) focal type of papillary muscle fibrosis, evidently a healed infarct of the papillary muscle present in 13% of the autopsies, is a histologically characteristic lesion associated with coronary artery disease and healed myocardial infarction; (2) diffuse type of papillary muscle fibrosis, probably an aging change present in almost half of the autopsies, is associated with sclerosis of the arteries in the papillary muscle, is identifiable histologically; and apparently is not associated with any cardiac abnormality; and (3) focal cardiac myocytolysis, a unique histologic lesion, usually multifocal without predilection for any area of the heart, is associated with ischemic heart disease, death due to cancer complicated by non-bacterial thrombotic endocarditis and microthrombi in small cardiac arteries as well as with other diseases. Differentiation of the 2 types of papillary muscle fibrosis is important in the study of papillary muscle and mitral valve dysfunction. Focal cardiac myocytolysis may contribute to the fatal extension of myocardial infarcts.
Authors:
Steer, A; [1]  Nakashima, N; Kawashima, T; Lee, K K; Danzig, M D; Robertson, T L; Dock, D S
  1. Hijiyanna Park, Hiroshima JP
Publication Date:
Nov 01, 1977
Product Type:
Journal Article
Reference Number:
ERA-05-001851; EDB-79-133059
Resource Relation:
Journal Name: Shinzo; (Japan); Journal Volume: 18:6
Subject:
59 BASIC BIOLOGICAL SCIENCES; CARDIOVASCULAR DISEASES; AGING; AUTOPSY; FIBROSIS; HEART; ISCHEMIA; MAN; MYOCARDIAL INFARCTION; PATHOLOGICAL CHANGES; THROMBOSIS; ANEMIAS; ANIMALS; BODY; CARDIOVASCULAR SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; HEMIC DISEASES; MAMMALS; ORGANS; PRIMATES; SYMPTOMS; VERTEBRATES; 550900* - Pathology
OSTI ID:
5820965
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: SHZOA
Submitting Site:
TIC
Size:
Pages: 812-822
Announcement Date:

Journal Article:

Citation Formats

Steer, A, Nakashima, N, Kawashima, T, Lee, K K, Danzig, M D, Robertson, T L, and Dock, D S. Small cardiac lesions: fibrosis of papillary muscles and focal cardiac myocytolysis. Japan: N. p., 1977. Web.
Steer, A, Nakashima, N, Kawashima, T, Lee, K K, Danzig, M D, Robertson, T L, & Dock, D S. Small cardiac lesions: fibrosis of papillary muscles and focal cardiac myocytolysis. Japan.
Steer, A, Nakashima, N, Kawashima, T, Lee, K K, Danzig, M D, Robertson, T L, and Dock, D S. 1977. "Small cardiac lesions: fibrosis of papillary muscles and focal cardiac myocytolysis." Japan.
@misc{etde_5820965,
title = {Small cardiac lesions: fibrosis of papillary muscles and focal cardiac myocytolysis}
author = {Steer, A, Nakashima, N, Kawashima, T, Lee, K K, Danzig, M D, Robertson, T L, and Dock, D S}
abstractNote = {Three types of small cardiac lesions were described and illustrated: (1) focal type of papillary muscle fibrosis, evidently a healed infarct of the papillary muscle present in 13% of the autopsies, is a histologically characteristic lesion associated with coronary artery disease and healed myocardial infarction; (2) diffuse type of papillary muscle fibrosis, probably an aging change present in almost half of the autopsies, is associated with sclerosis of the arteries in the papillary muscle, is identifiable histologically; and apparently is not associated with any cardiac abnormality; and (3) focal cardiac myocytolysis, a unique histologic lesion, usually multifocal without predilection for any area of the heart, is associated with ischemic heart disease, death due to cancer complicated by non-bacterial thrombotic endocarditis and microthrombi in small cardiac arteries as well as with other diseases. Differentiation of the 2 types of papillary muscle fibrosis is important in the study of papillary muscle and mitral valve dysfunction. Focal cardiac myocytolysis may contribute to the fatal extension of myocardial infarcts.}
journal = {Shinzo; (Japan)}
volume = {18:6}
journal type = {AC}
place = {Japan}
year = {1977}
month = {Nov}
}