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Hemodynamic evaluation in patients with superficial temporal artery-middle cerebral artery anastomosis; Stable xenon CT-CBF study and acetazolamide

Abstract

Sixteen patients with minor completed stroke in the chronic stage underwent superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis. The acetazolamide-activated regional cerebral blood flow (rCBF) was measured 20 minutes after the injection using inhalation of stable xenon and computed tomographic scanning (Xe{sup s} CT-CBF study) pre- and postoperatively. Eleven patients (Group 1) showed immediate improvement in neurological state within a few days of the operation, while five (Group 2) showed no improvements. Preoperative rCBF in the ischemic areas without infarction was 30.8+-3.0 ml/100 gm/min in Group 1 and 53.0+-5.2 ml/100 gm/min in Group 2. Preoperative vasodilatory capacity with acetazolamide in Group 1 was 5.7+-8.6 and significantly increased to 19.8+-4.9 after surgery. In Group 2, pre- and postoperative vasodilatory capacity was 12.7+-3.1 and 14.9+-2.9, respectively, and there was no significant change. These results suggested that minor stroke patients with moderate decrease of affected side rCBF (less than 40 ml/100 gm/min) and with hemodynamic impairment may have the surgical indication for STA-MCA anastomosis. (author).
Authors:
Touho, Hajime; Karasawa, Jun; Shishido, Hisashi; Morisako, Toshitaka; Yamada, Keisuke; Shibamoto, Keiji [1] 
  1. Osaka Neurological Inst., Toyonaka (Japan)
Publication Date:
Dec 01, 1990
Product Type:
Journal Article
Reference Number:
JPN-91-005324; EDB-91-090746
Resource Relation:
Journal Name: Neurologia Medico-Chirurgica; (Japan); Journal Volume: 30:13
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CEREBRUM; CAT SCANNING; ACETAMIDE; ARTERIES; BLOOD FLOW; SURGERY; VASCULAR DISEASES; VASODILATION; XENON; AMIDES; BLOOD VESSELS; BODY; BRAIN; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; ELEMENTS; FLUIDS; GASES; MEDICINE; NERVOUS SYSTEM; NONMETALS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; RARE GASES; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5801704
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0387-2572; CODEN: NMCHB
Submitting Site:
JPN
Size:
Pages: 1003-1010
Announcement Date:
Jul 15, 1991

Citation Formats

Touho, Hajime, Karasawa, Jun, Shishido, Hisashi, Morisako, Toshitaka, Yamada, Keisuke, and Shibamoto, Keiji. Hemodynamic evaluation in patients with superficial temporal artery-middle cerebral artery anastomosis; Stable xenon CT-CBF study and acetazolamide. Japan: N. p., 1990. Web.
Touho, Hajime, Karasawa, Jun, Shishido, Hisashi, Morisako, Toshitaka, Yamada, Keisuke, & Shibamoto, Keiji. Hemodynamic evaluation in patients with superficial temporal artery-middle cerebral artery anastomosis; Stable xenon CT-CBF study and acetazolamide. Japan.
Touho, Hajime, Karasawa, Jun, Shishido, Hisashi, Morisako, Toshitaka, Yamada, Keisuke, and Shibamoto, Keiji. 1990. "Hemodynamic evaluation in patients with superficial temporal artery-middle cerebral artery anastomosis; Stable xenon CT-CBF study and acetazolamide." Japan.
@misc{etde_5801704,
title = {Hemodynamic evaluation in patients with superficial temporal artery-middle cerebral artery anastomosis; Stable xenon CT-CBF study and acetazolamide}
author = {Touho, Hajime, Karasawa, Jun, Shishido, Hisashi, Morisako, Toshitaka, Yamada, Keisuke, and Shibamoto, Keiji}
abstractNote = {Sixteen patients with minor completed stroke in the chronic stage underwent superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis. The acetazolamide-activated regional cerebral blood flow (rCBF) was measured 20 minutes after the injection using inhalation of stable xenon and computed tomographic scanning (Xe{sup s} CT-CBF study) pre- and postoperatively. Eleven patients (Group 1) showed immediate improvement in neurological state within a few days of the operation, while five (Group 2) showed no improvements. Preoperative rCBF in the ischemic areas without infarction was 30.8+-3.0 ml/100 gm/min in Group 1 and 53.0+-5.2 ml/100 gm/min in Group 2. Preoperative vasodilatory capacity with acetazolamide in Group 1 was 5.7+-8.6 and significantly increased to 19.8+-4.9 after surgery. In Group 2, pre- and postoperative vasodilatory capacity was 12.7+-3.1 and 14.9+-2.9, respectively, and there was no significant change. These results suggested that minor stroke patients with moderate decrease of affected side rCBF (less than 40 ml/100 gm/min) and with hemodynamic impairment may have the surgical indication for STA-MCA anastomosis. (author).}
journal = []
volume = {30:13}
journal type = {AC}
place = {Japan}
year = {1990}
month = {Dec}
}