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(/sup 125/I) 7-iodo-6-demethyl-6-deoxytetracycline HCl: its use in the study of bone mineralization

Abstract

/sup 125/I 7-iodo-6-demethyl-6-deoxytetracycline can be used in a non-invasive method to indicate sites of active bone mineralization. Sequential doses of this agent have been used to follow bone repair in a fractured femur of a dog without resorting to bone biopsy. Metabolic problems that involve bone may also be studied with this potentially useful radiopharmaceutical.
Authors:
Belbeck, L W; Bowen, B M; Garnett, E S; [1]  Porter, J K; Teare, F W
  1. McMaster Univ., Hamilton, Ontario (Canada)
Publication Date:
Jun 01, 1979
Product Type:
Journal Article
Reference Number:
AIX-10-484721; EDB-80-024119
Resource Relation:
Journal Name: Int. J. Appl. Radiat. Isot.; (United Kingdom); Journal Volume: 30:6
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; BONE TISSUES; BIOLOGICAL REPAIR; FEMUR; MINERALIZATION; IODINE 125; RADIONUCLIDE KINETICS; BIOLOGICAL LOCALIZATION; DOGS; HYDROCHLORIC ACID; INTRAPERITONEAL INJECTION; METABOLISM; OXYTETRACYCLINE; RADIOPHARMACEUTICALS; ANIMALS; ANTIBIOTICS; BETA DECAY RADIOISOTOPES; BIOLOGICAL RECOVERY; BODY; CONNECTIVE TISSUE; DAYS LIVING RADIOISOTOPES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; HYDROGEN COMPOUNDS; INJECTION; INORGANIC ACIDS; INTAKE; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RECOVERY; REPAIR; SKELETON; TETRACYCLINES; TISSUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550501 - Metabolism- Tracer Techniques
OSTI ID:
5798114
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: IJARA
Submitting Site:
INIS
Size:
Pages: 369-373
Announcement Date:
Jan 01, 1980

Citation Formats

Belbeck, L W, Bowen, B M, Garnett, E S, Porter, J K, and Teare, F W. (/sup 125/I) 7-iodo-6-demethyl-6-deoxytetracycline HCl: its use in the study of bone mineralization. United Kingdom: N. p., 1979. Web. doi:10.1016/0020-708X(79)90022-X.
Belbeck, L W, Bowen, B M, Garnett, E S, Porter, J K, & Teare, F W. (/sup 125/I) 7-iodo-6-demethyl-6-deoxytetracycline HCl: its use in the study of bone mineralization. United Kingdom. https://doi.org/10.1016/0020-708X(79)90022-X
Belbeck, L W, Bowen, B M, Garnett, E S, Porter, J K, and Teare, F W. 1979. "(/sup 125/I) 7-iodo-6-demethyl-6-deoxytetracycline HCl: its use in the study of bone mineralization." United Kingdom. https://doi.org/10.1016/0020-708X(79)90022-X.
@misc{etde_5798114,
title = {(/sup 125/I) 7-iodo-6-demethyl-6-deoxytetracycline HCl: its use in the study of bone mineralization}
author = {Belbeck, L W, Bowen, B M, Garnett, E S, Porter, J K, and Teare, F W}
abstractNote = {/sup 125/I 7-iodo-6-demethyl-6-deoxytetracycline can be used in a non-invasive method to indicate sites of active bone mineralization. Sequential doses of this agent have been used to follow bone repair in a fractured femur of a dog without resorting to bone biopsy. Metabolic problems that involve bone may also be studied with this potentially useful radiopharmaceutical.}
doi = {10.1016/0020-708X(79)90022-X}
journal = []
volume = {30:6}
journal type = {AC}
place = {United Kingdom}
year = {1979}
month = {Jun}
}