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RBE determination of tumors by serum aldolase

Abstract

In patients with histologically ascertained bronchial carcinoma the tumor volume and the plasma volume was determined before therapy. Following the first irradiation of the tumor with a /sup 60/Co pendulum technique over the diseased side with 5 Gy for the 80% isodose determination of aldolase and creatin kinase was performed frequently during 24 h. A peak of serum aldolase was found 16 - 18 h after irradiation. The aldolase values of this peak were higher for undifferentiated carcinomas than for squamous cell carcinomas and proportional to the size of the tumor. The hypothesis is made that by means of this method using different radiation qualities their 'relative biological effectiveness' can be determined.
Authors:
Dalluege, K H [1] 
  1. Akademie der Wissenschaften der DDR, Berlin. Zentralinstitut fuer Krebsforschung
Publication Date:
Jun 01, 1981
Product Type:
Journal Article
Reference Number:
AIX-13-653796; EDB-82-060224
Resource Relation:
Journal Name: Radiobiol., Radiother.; (German Democratic Republic); Journal Volume: 22:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ALDOLASE; BIOLOGICAL RADIATION EFFECTS; BRONCHI; RADIOTHERAPY; CARCINOMAS; RBE; PHOSPHOTRANSFERASES; BLOOD SERUM; COBALT 60; CREATINE; GAMMA RADIATION; PATIENTS; RESPIRATORY SYSTEM DISEASES; TIME DEPENDENCE; ALDEHYDE-LYASES; AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; CARBON-CARBON LYASES; CARBOXYLIC ACIDS; COBALT ISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; ENZYMES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LYASES; MEDICINE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; PHOSPHORUS-GROUP TRANSFERASES; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY; TRANSFERASES; YEARS LIVING RADIOISOTOPES; 550603* - Medicine- External Radiation in Therapy- (1980-); 560115 - Radiation Effects on Biochemicals- In Man- (-1987)
OSTI ID:
5796327
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: RDBGA
Submitting Site:
INIS
Size:
Pages: 253-255
Announcement Date:
Feb 01, 1982

Citation Formats

Dalluege, K H. RBE determination of tumors by serum aldolase. Germany: N. p., 1981. Web.
Dalluege, K H. RBE determination of tumors by serum aldolase. Germany.
Dalluege, K H. 1981. "RBE determination of tumors by serum aldolase." Germany.
@misc{etde_5796327,
title = {RBE determination of tumors by serum aldolase}
author = {Dalluege, K H}
abstractNote = {In patients with histologically ascertained bronchial carcinoma the tumor volume and the plasma volume was determined before therapy. Following the first irradiation of the tumor with a /sup 60/Co pendulum technique over the diseased side with 5 Gy for the 80% isodose determination of aldolase and creatin kinase was performed frequently during 24 h. A peak of serum aldolase was found 16 - 18 h after irradiation. The aldolase values of this peak were higher for undifferentiated carcinomas than for squamous cell carcinomas and proportional to the size of the tumor. The hypothesis is made that by means of this method using different radiation qualities their 'relative biological effectiveness' can be determined.}
journal = []
volume = {22:3}
journal type = {AC}
place = {Germany}
year = {1981}
month = {Jun}
}