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Effects of combined irradiation and hyperthermia on creatine kinase activity in rat tissues

Journal Article:

Abstract

The effects of different doses of beta- and X-irradiations on creatine kinase activity (CKA) in cerebrum and liver of rats were investigated under hyperthermia conditions. Beta irradiation was carried out at 2.50, 3.05, 4.45 or 7.40 Krad doses under heat load. After withdrawal of the animals from the chamber they were exposed to 25,50,100,250 or 400 R X-ray doses (for beta irradiation 2.50,2.50,3.05,4.45 or 7.40 Krad, respectively). In 5,12,19 and 26 days after exposure the animals were decapitated and CKA of aqueous extracts of cerebral hemispheres and livers were determined. It has been established, that the thermal stress decreases the radiosensitivity of cerebral CKA, but intensifies the irradiation consequences in respect to liver activity.
Authors:
Matyushichev, V B; Taratukhin, V P; Shamratova, V G; Yuzhakova, G A [1] 
  1. Leningradskij Gosudarstvennyj Univ. (USSR)
Publication Date:
Sep 01, 1977
Product Type:
Journal Article
Reference Number:
AIX-10-433008; EDB-79-138145
Resource Relation:
Journal Name: Tsitologiya; (USSR); Journal Volume: 19:9
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BRAIN; ENZYME ACTIVITY; RADIOSENSITIVITY; HYPERTHERMIA; RADIOSENSITIVITY EFFECTS; LIVER; PHOSPHOTRANSFERASES; BIOLOGICAL RADIATION EFFECTS; TEMPERATURE DEPENDENCE; BETA PARTICLES; COMPARATIVE EVALUATIONS; RADIATION DOSES; RATS; WHOLE-BODY IRRADIATION; X RADIATION; ANIMALS; BIOLOGICAL EFFECTS; BODY; BODY TEMPERATURE; CENTRAL NERVOUS SYSTEM; CHARGED PARTICLES; DIGESTIVE SYSTEM; DOSES; ELECTROMAGNETIC RADIATION; ENZYMES; EXTERNAL IRRADIATION; GLANDS; IONIZING RADIATIONS; IRRADIATION; MAMMALS; NERVOUS SYSTEM; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; TRANSFERASES; VERTEBRATES; 560114* - Radiation Effects on Biochemicals- In Animals- (-1987); 560152 - Radiation Effects on Animals- Animals
OSTI ID:
5792737
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: TSITA
Submitting Site:
INIS
Size:
Pages: 1069-1071
Announcement Date:

Journal Article:

Citation Formats

Matyushichev, V B, Taratukhin, V P, Shamratova, V G, and Yuzhakova, G A. Effects of combined irradiation and hyperthermia on creatine kinase activity in rat tissues. USSR: N. p., 1977. Web.
Matyushichev, V B, Taratukhin, V P, Shamratova, V G, & Yuzhakova, G A. Effects of combined irradiation and hyperthermia on creatine kinase activity in rat tissues. USSR.
Matyushichev, V B, Taratukhin, V P, Shamratova, V G, and Yuzhakova, G A. 1977. "Effects of combined irradiation and hyperthermia on creatine kinase activity in rat tissues." USSR.
@misc{etde_5792737,
title = {Effects of combined irradiation and hyperthermia on creatine kinase activity in rat tissues}
author = {Matyushichev, V B, Taratukhin, V P, Shamratova, V G, and Yuzhakova, G A}
abstractNote = {The effects of different doses of beta- and X-irradiations on creatine kinase activity (CKA) in cerebrum and liver of rats were investigated under hyperthermia conditions. Beta irradiation was carried out at 2.50, 3.05, 4.45 or 7.40 Krad doses under heat load. After withdrawal of the animals from the chamber they were exposed to 25,50,100,250 or 400 R X-ray doses (for beta irradiation 2.50,2.50,3.05,4.45 or 7.40 Krad, respectively). In 5,12,19 and 26 days after exposure the animals were decapitated and CKA of aqueous extracts of cerebral hemispheres and livers were determined. It has been established, that the thermal stress decreases the radiosensitivity of cerebral CKA, but intensifies the irradiation consequences in respect to liver activity.}
journal = {Tsitologiya; (USSR)}
volume = {19:9}
journal type = {AC}
place = {USSR}
year = {1977}
month = {Sep}
}