Abstract
Semi-quantitative analysis (e.g. optical density ratios) of (/sup 14/C)2-deoxyglucose autoradiograms is widely used in neuroscience research. The authors demonstrate that a fixed ratio of /sup 14/C-concentrations in the CNS does not yield a constant optical density ratio but is dependent upon the exposure time in the preparation of the autoradiograms and the absolute amounts of /sup 14/C from which the concentration ratio is derived. The failure of a fixed glucose utilization ratio to result in a constant optical density ratio represents a major interpretative difficulty in investigations where only semi-quantitative analysis of (/sup 14/C)2-deoxyglucose autoradiograms is undertaken.
Citation Formats
Kelly, P T, and McCulloch, J.
Critical appraisal of semi-quantitative analysis of 2-deoxyglucose autoradiograms.
Netherlands: N. p.,
1983.
Web.
Kelly, P T, & McCulloch, J.
Critical appraisal of semi-quantitative analysis of 2-deoxyglucose autoradiograms.
Netherlands.
Kelly, P T, and McCulloch, J.
1983.
"Critical appraisal of semi-quantitative analysis of 2-deoxyglucose autoradiograms."
Netherlands.
@misc{etde_5776308,
title = {Critical appraisal of semi-quantitative analysis of 2-deoxyglucose autoradiograms}
author = {Kelly, P T, and McCulloch, J}
abstractNote = {Semi-quantitative analysis (e.g. optical density ratios) of (/sup 14/C)2-deoxyglucose autoradiograms is widely used in neuroscience research. The authors demonstrate that a fixed ratio of /sup 14/C-concentrations in the CNS does not yield a constant optical density ratio but is dependent upon the exposure time in the preparation of the autoradiograms and the absolute amounts of /sup 14/C from which the concentration ratio is derived. The failure of a fixed glucose utilization ratio to result in a constant optical density ratio represents a major interpretative difficulty in investigations where only semi-quantitative analysis of (/sup 14/C)2-deoxyglucose autoradiograms is undertaken.}
journal = []
volume = {269:1}
journal type = {AC}
place = {Netherlands}
year = {1983}
month = {Jun}
}
title = {Critical appraisal of semi-quantitative analysis of 2-deoxyglucose autoradiograms}
author = {Kelly, P T, and McCulloch, J}
abstractNote = {Semi-quantitative analysis (e.g. optical density ratios) of (/sup 14/C)2-deoxyglucose autoradiograms is widely used in neuroscience research. The authors demonstrate that a fixed ratio of /sup 14/C-concentrations in the CNS does not yield a constant optical density ratio but is dependent upon the exposure time in the preparation of the autoradiograms and the absolute amounts of /sup 14/C from which the concentration ratio is derived. The failure of a fixed glucose utilization ratio to result in a constant optical density ratio represents a major interpretative difficulty in investigations where only semi-quantitative analysis of (/sup 14/C)2-deoxyglucose autoradiograms is undertaken.}
journal = []
volume = {269:1}
journal type = {AC}
place = {Netherlands}
year = {1983}
month = {Jun}
}