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Radioimmunoassay (RIA), a highly specific, extremely sensitive quantitative method of analysis

Abstract

Radioimmunoassay is an analytical method combining the sensitivity of radioactivity measurements and the specificity of the antigen-antibody-reaction. Thus, substances can be measured in concentrations as low as picograms per milliliter serum besides a millionfold excess of otherwise disturbing material (for example in serum). The method is simple to perform and is at present mainly used in the field of endocrinology. Further areas of possible application are in the diagnosis of infectious disease, drug research, environmental protection, forensic medicine as well as general analytics. Quantities of radioactivity, exclusively used in vitro, are in the nano-Curie range. Therefore the radiation dose is negligible.
Authors:
Strecker, H; Hachmann, H; Seidel, L [1] 
  1. Farbwerke Hoechst A.G., Frankfurt am Main (Germany, F.R.). Radiochemisches Lab.
Publication Date:
Feb 01, 1979
Product Type:
Journal Article
Reference Number:
AIX-10-466268; EDB-80-002352
Resource Relation:
Journal Name: Chem. Ztg.; (Germany, Federal Republic of); Journal Volume: 103:2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; RADIOIMMUNOASSAY; REVIEWS; ANTIGEN-ANTIBODY REACTIONS; DIAGNOSIS; ENZYMES; IN VITRO; INSULIN; IODINE 125; LABELLED COMPOUNDS; LIMITING VALUES; QUANTITY RATIO; RADIOASSAY; SENSITIVITY; USES; BETA DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; DOCUMENT TYPES; ELECTRON CAPTURE RADIOISOTOPES; HORMONES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; PEPTIDE HORMONES; RADIOISOTOPES; TRACER TECHNIQUES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5775046
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: CMKZA
Submitting Site:
INIS
Size:
Pages: 53-68
Announcement Date:
Aug 01, 1979

Citation Formats

Strecker, H, Hachmann, H, and Seidel, L. Radioimmunoassay (RIA), a highly specific, extremely sensitive quantitative method of analysis. Germany: N. p., 1979. Web.
Strecker, H, Hachmann, H, & Seidel, L. Radioimmunoassay (RIA), a highly specific, extremely sensitive quantitative method of analysis. Germany.
Strecker, H, Hachmann, H, and Seidel, L. 1979. "Radioimmunoassay (RIA), a highly specific, extremely sensitive quantitative method of analysis." Germany.
@misc{etde_5775046,
title = {Radioimmunoassay (RIA), a highly specific, extremely sensitive quantitative method of analysis}
author = {Strecker, H, Hachmann, H, and Seidel, L}
abstractNote = {Radioimmunoassay is an analytical method combining the sensitivity of radioactivity measurements and the specificity of the antigen-antibody-reaction. Thus, substances can be measured in concentrations as low as picograms per milliliter serum besides a millionfold excess of otherwise disturbing material (for example in serum). The method is simple to perform and is at present mainly used in the field of endocrinology. Further areas of possible application are in the diagnosis of infectious disease, drug research, environmental protection, forensic medicine as well as general analytics. Quantities of radioactivity, exclusively used in vitro, are in the nano-Curie range. Therefore the radiation dose is negligible.}
journal = []
volume = {103:2}
journal type = {AC}
place = {Germany}
year = {1979}
month = {Feb}
}