Abstract
The metabolic fate of the radioactive carbon in the [sup 14]C-urea breath test for Helicobacter pylori was investigated in 18 subjects. After ingestion of labelled urea, breath was sampled for 24 h, and urine was collected for 3 days. Subjects were designated high or low expirers on the basis of their breath counts, and this agreed well with H. pylori serologic analyses. When given 185 or 37 kBq of [sup 14]C-urea, 51% of the label was recovered from the breath of high expirers, and 7% from the breath of low expirers. The mean combined urinary and breath recovery for high expirers was 86%, and for low expirers it was 97%. It is concluded that the long-term retention of [sup 14]C from ingested [sup 14]C-urea is low. The results enable a more accurate estimation to be made of radiation exposure resulting from the [sup 14]C-urea breath test. 16 refs., 3 figs., 2 tabs.
Munster, D J;
Chapman, B A;
Burt, M J;
Dobbs, B R;
Allardyce, R A;
Bagshaw, P F;
Troughton, W D;
Cook, H B
[1]
- Christchurch Hospital (New Zealand)
Citation Formats
Munster, D J, Chapman, B A, Burt, M J, Dobbs, B R, Allardyce, R A, Bagshaw, P F, Troughton, W D, and Cook, H B.
The fate of ingested [sup 14]C-urea in the urea breath test for Helicobacter pylori infection.
Norway: N. p.,
1993.
Web.
Munster, D J, Chapman, B A, Burt, M J, Dobbs, B R, Allardyce, R A, Bagshaw, P F, Troughton, W D, & Cook, H B.
The fate of ingested [sup 14]C-urea in the urea breath test for Helicobacter pylori infection.
Norway.
Munster, D J, Chapman, B A, Burt, M J, Dobbs, B R, Allardyce, R A, Bagshaw, P F, Troughton, W D, and Cook, H B.
1993.
"The fate of ingested [sup 14]C-urea in the urea breath test for Helicobacter pylori infection."
Norway.
@misc{etde_5759009,
title = {The fate of ingested [sup 14]C-urea in the urea breath test for Helicobacter pylori infection}
author = {Munster, D J, Chapman, B A, Burt, M J, Dobbs, B R, Allardyce, R A, Bagshaw, P F, Troughton, W D, and Cook, H B}
abstractNote = {The metabolic fate of the radioactive carbon in the [sup 14]C-urea breath test for Helicobacter pylori was investigated in 18 subjects. After ingestion of labelled urea, breath was sampled for 24 h, and urine was collected for 3 days. Subjects were designated high or low expirers on the basis of their breath counts, and this agreed well with H. pylori serologic analyses. When given 185 or 37 kBq of [sup 14]C-urea, 51% of the label was recovered from the breath of high expirers, and 7% from the breath of low expirers. The mean combined urinary and breath recovery for high expirers was 86%, and for low expirers it was 97%. It is concluded that the long-term retention of [sup 14]C from ingested [sup 14]C-urea is low. The results enable a more accurate estimation to be made of radiation exposure resulting from the [sup 14]C-urea breath test. 16 refs., 3 figs., 2 tabs.}
journal = []
volume = {28:8}
journal type = {AC}
place = {Norway}
year = {1993}
month = {Aug}
}
title = {The fate of ingested [sup 14]C-urea in the urea breath test for Helicobacter pylori infection}
author = {Munster, D J, Chapman, B A, Burt, M J, Dobbs, B R, Allardyce, R A, Bagshaw, P F, Troughton, W D, and Cook, H B}
abstractNote = {The metabolic fate of the radioactive carbon in the [sup 14]C-urea breath test for Helicobacter pylori was investigated in 18 subjects. After ingestion of labelled urea, breath was sampled for 24 h, and urine was collected for 3 days. Subjects were designated high or low expirers on the basis of their breath counts, and this agreed well with H. pylori serologic analyses. When given 185 or 37 kBq of [sup 14]C-urea, 51% of the label was recovered from the breath of high expirers, and 7% from the breath of low expirers. The mean combined urinary and breath recovery for high expirers was 86%, and for low expirers it was 97%. It is concluded that the long-term retention of [sup 14]C from ingested [sup 14]C-urea is low. The results enable a more accurate estimation to be made of radiation exposure resulting from the [sup 14]C-urea breath test. 16 refs., 3 figs., 2 tabs.}
journal = []
volume = {28:8}
journal type = {AC}
place = {Norway}
year = {1993}
month = {Aug}
}