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Myocardial infarct size vs duration of coronary artery occlusion in patients with acute anterior myocardial infarction. Assessment by thallium-201 emission tomography, gated cardiac pool study and CK-MB release

Journal Article:

Abstract

Relationship between the duration of coronary artery occlusion and myocardial infarct size was investigated in 24 patients with acute anterior myocardial infarction associated with occlusion of the left anterior descending artery. The duration of coronary artery occlusion was divided into (A) 4 hours or less, (B) 4-10 hours, and (C) 10 hours or more. Defect score obtained by thallium-201 emission computed tomography was significantly greater, and left ventricular ejection fraction was significantly lower as the duration of coronary artery occlusion increased. Creatine kinase-MB (..sigma..CK-MB) was higher in cases of longer duration of occlusion. However, this was not significant between the groups A and B, suggesting the influence of reperfusion on the ..sigma..CK-MB release. The duration of coronary artery occlusion was considered to be an important factor to determine the infarct size, and significance of early reperfusion was suggested.
Authors:
Tamaki, Shunichi; Kambara, Hirofumi; Kadota, Kazunori; Murakami, Tomoyuki; Suzuki, Yukisono [1] 
  1. Kyoto Univ. (Japan). Faculty of Medicine
Publication Date:
Mar 01, 1984
Product Type:
Journal Article
Reference Number:
AIX-16-024147; EDB-85-097576
Resource Relation:
Journal Name: Kokyu To Junkan; (Japan); Journal Volume: 32:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MYOCARDIAL INFARCTION; TIME DEPENDENCE; MYOCARDIUM; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; RADIOCARDIOGRAPHY; TECHNETIUM 99; DIAGNOSTIC USES; THALLIUM 201; BLOOD CIRCULATION; CHEMOTHERAPY; CORONARIES; CREATINE; DIAGNOSIS; DYNAMIC FUNCTION STUDIES; PATIENTS; UROKINASE; AMINO ACIDS; ARTERIES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BLOOD VESSELS; BODY; CARBOXYLIC ACIDS; CARDIOGRAPHY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; COMPUTERIZED TOMOGRAPHY; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EMISSION COMPUTED TOMOGRAPHY; ENZYMES; FIBRINOLYTIC AGENTS; HEART; HEAVY NUCLEI; HEMATOLOGIC AGENTS; HOURS LIVING RADIOISOTOPES; HYDROLASES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MUSCLES; NONSPECIFIC PEPTIDASES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HYDROLASES; RADIOISOTOPES; SECONDS LIVING RADIOISOTOPES; TECHNETIUM ISOTOPES; THALLIUM ISOTOPES; THERAPY; TOMOGRAPHY; USES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5753704
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KOJUA
Submitting Site:
HEDB
Size:
Pages: 235-240
Announcement Date:

Journal Article:

Citation Formats

Tamaki, Shunichi, Kambara, Hirofumi, Kadota, Kazunori, Murakami, Tomoyuki, and Suzuki, Yukisono. Myocardial infarct size vs duration of coronary artery occlusion in patients with acute anterior myocardial infarction. Assessment by thallium-201 emission tomography, gated cardiac pool study and CK-MB release. Japan: N. p., 1984. Web.
Tamaki, Shunichi, Kambara, Hirofumi, Kadota, Kazunori, Murakami, Tomoyuki, & Suzuki, Yukisono. Myocardial infarct size vs duration of coronary artery occlusion in patients with acute anterior myocardial infarction. Assessment by thallium-201 emission tomography, gated cardiac pool study and CK-MB release. Japan.
Tamaki, Shunichi, Kambara, Hirofumi, Kadota, Kazunori, Murakami, Tomoyuki, and Suzuki, Yukisono. 1984. "Myocardial infarct size vs duration of coronary artery occlusion in patients with acute anterior myocardial infarction. Assessment by thallium-201 emission tomography, gated cardiac pool study and CK-MB release." Japan.
@misc{etde_5753704,
title = {Myocardial infarct size vs duration of coronary artery occlusion in patients with acute anterior myocardial infarction. Assessment by thallium-201 emission tomography, gated cardiac pool study and CK-MB release}
author = {Tamaki, Shunichi, Kambara, Hirofumi, Kadota, Kazunori, Murakami, Tomoyuki, and Suzuki, Yukisono}
abstractNote = {Relationship between the duration of coronary artery occlusion and myocardial infarct size was investigated in 24 patients with acute anterior myocardial infarction associated with occlusion of the left anterior descending artery. The duration of coronary artery occlusion was divided into (A) 4 hours or less, (B) 4-10 hours, and (C) 10 hours or more. Defect score obtained by thallium-201 emission computed tomography was significantly greater, and left ventricular ejection fraction was significantly lower as the duration of coronary artery occlusion increased. Creatine kinase-MB (..sigma..CK-MB) was higher in cases of longer duration of occlusion. However, this was not significant between the groups A and B, suggesting the influence of reperfusion on the ..sigma..CK-MB release. The duration of coronary artery occlusion was considered to be an important factor to determine the infarct size, and significance of early reperfusion was suggested.}
journal = {Kokyu To Junkan; (Japan)}
volume = {32:3}
journal type = {AC}
place = {Japan}
year = {1984}
month = {Mar}
}